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| Description
| - Aim Small-fiber neuropathy (SFN) is reported to be associated with a range of diseases or conditions that are partly different from those associated with large-fiber affection. The aim of the study is to evaluate aetiology in a group of SFN patients in comparison with mixed (i.e., small- and large-) fiber neuropathy (MFN). Methods A detailed medical history was taken and exhaustive blood tests, chest radiography and lumbar puncture were performed in a group of 84 patients with “burning feet” syndrome and clearly proven affection of small nerve fibers (verified by abnormal thermal thresholds and reduced intra-epidermal nerve fiber density in the distal calf). Thirty-three of them also exhibited nerve conduction abnormalities as a sign of large-fibre involvement (MFN group). Results The range and proportions of causes were similar in SFN and MFN subgroups. Diabetes mellitus and chronic alcohol abuse were the most prominent aetiologies (33%; 15%), while further causes were less common and included monocl
- Aim Small-fiber neuropathy (SFN) is reported to be associated with a range of diseases or conditions that are partly different from those associated with large-fiber affection. The aim of the study is to evaluate aetiology in a group of SFN patients in comparison with mixed (i.e., small- and large-) fiber neuropathy (MFN). Methods A detailed medical history was taken and exhaustive blood tests, chest radiography and lumbar puncture were performed in a group of 84 patients with “burning feet” syndrome and clearly proven affection of small nerve fibers (verified by abnormal thermal thresholds and reduced intra-epidermal nerve fiber density in the distal calf). Thirty-three of them also exhibited nerve conduction abnormalities as a sign of large-fibre involvement (MFN group). Results The range and proportions of causes were similar in SFN and MFN subgroups. Diabetes mellitus and chronic alcohol abuse were the most prominent aetiologies (33%; 15%), while further causes were less common and included monocl (en)
- Cíl. Neuropatie tenkých vláken (SFN) je dle literatury asociována s širokým spektrem nemocí a stavů, které se zčásti liší od těch asociovaných s postiženíh silných vláken. Cílem bylo zjistit etiologii ve skupině pacientů s postižením typu SFN ve srovnání se skupinou s postižením jak tenkých, tak silných vláken - smíšený typ neuropatie (MFN). Methoda. Byla odebrána detailní anamnéza a provedeny rozsáhlé serologické testy, RTG hrudníku a lumbální punkce byly provedeny u skupině 84 nemocných se syndromem pálivé bolesti v nohou "burning feet" a jasně prokázanou afekcí tenkých vláken verifikovanou pomocí abnormálního termického prahu a sníženou intraepidermální hustotou v distální části bérce. U 33 pacientů byly navíc přítomny abnormality kondukčních studií jako známka současného postižení silných vláken (skupina smíšené neuropatie - MFN). Výsledky. Spektrum a podíl příčin byly podobné ve skupině SFN a MFN. Diabetes mellitus a chronický abusus alkoholu byly nejčastějšími příčinami (33%; 15%), zat (cs)
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| Title
| - Aetiology of small- and mixed-fiber neuropathy
- Etiologie neuropatie tenkých vláken a smíšené neuropatie (cs)
- Aetiology of small- and mixed-fiber neuropathy (en)
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| skos:prefLabel
| - Aetiology of small- and mixed-fiber neuropathy
- Etiologie neuropatie tenkých vláken a smíšené neuropatie (cs)
- Aetiology of small- and mixed-fiber neuropathy (en)
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| skos:notation
| - RIV/00216224:14110/06:00017809!RIV08-MSM-14110___
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14110/06:00017809
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - aetiology; small-fiber neuropathy; mixed-fiber neuropathy (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - European Journal of Neurology
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Bednařík, Josef
- Dušek, Ladislav
- Sommer, K.
- Vlčková, Eva
- Toyka, K.
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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| is http://linked.open...avai/riv/vysledek
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