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Description
| - Matrix metalloproteinase MMP-2 and its endogenous inhibitor TIMP-1 are associated with extracellular matrix remodeling, which may lead to interstitial fibrosis and thus contribute to heart failure. Besides, pro- and anti-fibrotic factors such as endothelin-1 and nitric oxide, respectively, regulate fibrosis by modulating collagen synthesis and also MMP/TIMP activity. Nowadays, there is thought that progressive remodeling accompanied with changes in the extracellular matrix may lead to severe heart failure. The aim of this study was to find a relationship between MMP-2/TIMP-1 and other above mentioned parameters in patients with heart failure.
- Matrix metalloproteinase MMP-2 and its endogenous inhibitor TIMP-1 are associated with extracellular matrix remodeling, which may lead to interstitial fibrosis and thus contribute to heart failure. Besides, pro- and anti-fibrotic factors such as endothelin-1 and nitric oxide, respectively, regulate fibrosis by modulating collagen synthesis and also MMP/TIMP activity. Nowadays, there is thought that progressive remodeling accompanied with changes in the extracellular matrix may lead to severe heart failure. The aim of this study was to find a relationship between MMP-2/TIMP-1 and other above mentioned parameters in patients with heart failure. (en)
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Title
| - Serum matrix metalloproteinase (MMP-2) and its tissue inhibitor (TIMP-1) in relation to pro- and anti-fibrotic factors in patients with heart failure
- Serum matrix metalloproteinase (MMP-2) and its tissue inhibitor (TIMP-1) in relation to pro- and anti-fibrotic factors in patients with heart failure (en)
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skos:prefLabel
| - Serum matrix metalloproteinase (MMP-2) and its tissue inhibitor (TIMP-1) in relation to pro- and anti-fibrotic factors in patients with heart failure
- Serum matrix metalloproteinase (MMP-2) and its tissue inhibitor (TIMP-1) in relation to pro- and anti-fibrotic factors in patients with heart failure (en)
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skos:notation
| - RIV/00216224:14110/06:00017183!RIV10-MSM-14110___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14110/06:00017183
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - metalloproteinase - tissue inhibitor - fibrotic factors - heart failure (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...v/mistoKonaniAkce
| - Piešťany, Slovak Republic
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http://linked.open...i/riv/mistoVydani
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http://linked.open...i/riv/nazevZdroje
| - Proceedings from XX. Biochemický zjazd
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...iv/tvurceVysledku
| - Tomandl, Josef
- Táborská, Eva
- Špinar, Jindřich
- Špinarová, Lenka
- Paulová, Hana
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http://linked.open...vavai/riv/typAkce
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http://linked.open.../riv/zahajeniAkce
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http://linked.open...n/vavai/riv/zamer
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number of pages
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http://purl.org/ne...btex#hasPublisher
| - Ústav molekulárnej fyziológie a genetiky SAV
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https://schema.org/isbn
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http://localhost/t...ganizacniJednotka
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is http://linked.open...avai/riv/vysledek
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