About: Vinca alkaloid effect on microtubules of HeLa cells.     Goto   Sponge   NotDistinct   Permalink

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  • The study evaluated the effect of selected vinca alkaloids on the microtubule network of heLa cells and the recovery of its disruption. Model experiments were used for demonstration of the quantification of microtubule network changes induced by vinca alkaloids using computer-assisted image analysis. Differences in the arrangement of microtubules were assessed by means of a software for quantification of the cytoskeleton changes in cells treated with vincristine at a concentration of 0,020 g/l and in untreated control cells. The microtubule network recovery process in time intervals of 6, 7, 8, 9, and 10 hours was quantified after treatment with vincristine at a concentration of 0,020 g/l for 60 min using the software for quantification of the cytoskeleton changes.
  • The study evaluated the effect of selected vinca alkaloids on the microtubule network of heLa cells and the recovery of its disruption. Model experiments were used for demonstration of the quantification of microtubule network changes induced by vinca alkaloids using computer-assisted image analysis. Differences in the arrangement of microtubules were assessed by means of a software for quantification of the cytoskeleton changes in cells treated with vincristine at a concentration of 0,020 g/l and in untreated control cells. The microtubule network recovery process in time intervals of 6, 7, 8, 9, and 10 hours was quantified after treatment with vincristine at a concentration of 0,020 g/l for 60 min using the software for quantification of the cytoskeleton changes. (en)
Title
  • Vinca alkaloid effect on microtubules of HeLa cells.
  • Vinca alkaloid effect on microtubules of HeLa cells. (en)
skos:prefLabel
  • Vinca alkaloid effect on microtubules of HeLa cells.
  • Vinca alkaloid effect on microtubules of HeLa cells. (en)
skos:notation
  • RIV/00216224:14110/06:00016405!RIV10-GA0-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GD301/03/H005)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 506102
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/06:00016405
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Cytoskeleton; Microtubule disruption; Cytoskeleton recovery; vincristine; vinblastine (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [5E6C1D18231E]
http://linked.open...i/riv/nazevZdroje
  • Scripta Medica
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 79
http://linked.open...iv/tvurceVysledku
  • Škorpíková, Jiřina
  • Janisch, Roman
  • Bečvářová, Pavlína
  • Nový, Jindřich
issn
  • 1211-3395
number of pages
http://localhost/t...ganizacniJednotka
  • 14110
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