About: UVC-Protective Effect of Caffeic Acid on Normal and Transformated Human Skin Cells in Vitro     Goto   Sponge   NotDistinct   Permalink

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Description
  • Possible UVC-protective properties of caffeic acid (CA), a plant phenolic compound with antioxidant activity, were investigated on human KF1 diploid fibroblast and A431 epidermoid carcinoma cell lines. Cell populations, untreated and treated by antioxidants (CA and á-tocopherol), were irradiated by UVC at the wavelength of 254 nm and their proliferation activity was determined by the MTT-assay. Results show a strong protective effect of CA at both concentrations used (55.5 and 165.5 ěM). This protective ability is probably based on the antioxidant and scavenging activities of CA, which seems to be more efficient than á-tocopherol in protection against cytotoxic effect caused by UVC-irradiation.
  • Possible UVC-protective properties of caffeic acid (CA), a plant phenolic compound with antioxidant activity, were investigated on human KF1 diploid fibroblast and A431 epidermoid carcinoma cell lines. Cell populations, untreated and treated by antioxidants (CA and á-tocopherol), were irradiated by UVC at the wavelength of 254 nm and their proliferation activity was determined by the MTT-assay. Results show a strong protective effect of CA at both concentrations used (55.5 and 165.5 ěM). This protective ability is probably based on the antioxidant and scavenging activities of CA, which seems to be more efficient than á-tocopherol in protection against cytotoxic effect caused by UVC-irradiation. (en)
  • Možné UVC-protektivní vlastnosti kyseliny kávové (CA), rostlinné fenolické sloučeniny s antioxidační aktivitou, byly zkoumány na lidských diploidních fibroblastech KF1 a epidermoidní karcinomové linii A431. (cs)
Title
  • UVC-Protective Effect of Caffeic Acid on Normal and Transformated Human Skin Cells in Vitro
  • UVC-Protective Effect of Caffeic Acid on Normal and Transformated Human Skin Cells in Vitro (en)
  • UVC-protektivní vliv kyseliny kávové na normální a transformované lidské kožní buňky in vitro. (cs)
skos:prefLabel
  • UVC-Protective Effect of Caffeic Acid on Normal and Transformated Human Skin Cells in Vitro
  • UVC-Protective Effect of Caffeic Acid on Normal and Transformated Human Skin Cells in Vitro (en)
  • UVC-protektivní vliv kyseliny kávové na normální a transformované lidské kožní buňky in vitro. (cs)
skos:notation
  • RIV/00216224:14110/03:00011396!RIV09-GA0-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA304/00/0403)
http://linked.open...iv/cisloPeriodika
  • 49
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 632542
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/03:00011396
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • UVC; caffeic acid; UV-protective effect; alpha-tocopherol (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [9A865D68DFEE]
http://linked.open...i/riv/nazevZdroje
  • Folia Biologica
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 2003
http://linked.open...iv/tvurceVysledku
  • Neradil, Jakub
  • Veselská, Renata
  • Slanina, Jiří
http://linked.open...ain/vavai/riv/wos
  • 000187034900004
issn
  • 0015-5500
number of pages
http://localhost/t...ganizacniJednotka
  • 14110
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