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Description
| - The study shows that both agonistic and antagonistic manipulation with cannabinoid CB1 as well as CB2 receptor caused changes in social behaviour in mice. Mixed CB1,2 agonists produced biphasic effects - stimulation of aggressive behaviour in timid mice at low doses and inhibition of aggressive activities in aggressive mice at high doses. Inhibitory influence on aggressive behaviour in aggressive mice was present also after all tested doses of selective CB1 agonist, was lower after CB2 agonist and was not apparent after administration of CB1 antagonist. Pro-aggressive effects in timid mice were elicited besides CB1,2 agonists also by both, CB1 and CB2 agonist. The effects of cannabinoid receptor ligands on leukocyte phagocytosis resemble those observed in behavioural studies as CB1,2 agonists produced biphasic influence - stimulation and suppression of phagocytic activity at low and high doses, respectively. Such effects were apparent also after administration of selective CB2 agonist but surprisingly
- The study shows that both agonistic and antagonistic manipulation with cannabinoid CB1 as well as CB2 receptor caused changes in social behaviour in mice. Mixed CB1,2 agonists produced biphasic effects - stimulation of aggressive behaviour in timid mice at low doses and inhibition of aggressive activities in aggressive mice at high doses. Inhibitory influence on aggressive behaviour in aggressive mice was present also after all tested doses of selective CB1 agonist, was lower after CB2 agonist and was not apparent after administration of CB1 antagonist. Pro-aggressive effects in timid mice were elicited besides CB1,2 agonists also by both, CB1 and CB2 agonist. The effects of cannabinoid receptor ligands on leukocyte phagocytosis resemble those observed in behavioural studies as CB1,2 agonists produced biphasic influence - stimulation and suppression of phagocytic activity at low and high doses, respectively. Such effects were apparent also after administration of selective CB2 agonist but surprisingly (en)
- The study shows that both agonistic and antagonistic manipulation with cannabinoid CB1 as well as CB2 receptor caused changes in social behaviour in mice. Mixed CB1,2 agonists produced biphasic effects - stimulation of aggressive behaviour in timid mice at low doses and inhibition of aggressive activities in aggressive mice at high doses. Inhibitory influence on aggressive behaviour in aggressive mice was present also after all tested doses of selective CB1 agonist, was lower after CB2 agonist and was not apparent after administration of CB1 antagonist. Pro-aggressive effects in timid mice were elicited besides CB1,2 agonists also by both, CB1 and CB2 agonist. The effects of cannabinoid receptor ligands on leukocyte phagocytosis resemble those observed in behavioural studies as CB1,2 agonists produced biphasic influence - stimulation and suppression of phagocytic activity at low and high doses, respectively. Such effects were apparent also after administration of selective CB2 agonist but surprisingly (cs)
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Title
| - Cannabinoids: effects on behaviour and leukocyte phagocytosis
- Cannabinoids: effects on behaviour and leukocyte phagocytosis (en)
- Cannabinoids: effects on behaviour and leukocyte phagocytosis (cs)
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skos:prefLabel
| - Cannabinoids: effects on behaviour and leukocyte phagocytosis
- Cannabinoids: effects on behaviour and leukocyte phagocytosis (en)
- Cannabinoids: effects on behaviour and leukocyte phagocytosis (cs)
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skos:notation
| - RIV/00216224:14110/02:00007827!RIV08-MSM-14110___
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14110/02:00007827
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - cannabinoids; cannabinoid CB1 and CB2 receptors; social behaviour; leukocyte phagocytosis; %22i.v. self-administration%22; mice; rats (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...v/mistoKonaniAkce
| - April 18 - 21, 2002, Brno, Czech Republic
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http://linked.open...i/riv/mistoVydani
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http://linked.open...i/riv/nazevZdroje
| - Abstracts of Workshop: Psychopharmacology of Cannabis and Ecstasy
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...iv/tvurceVysledku
| - Nováková, Jana
- Šulcová, Alexandra
- Vinklerová, Jana
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http://linked.open...vavai/riv/typAkce
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http://linked.open.../riv/zahajeniAkce
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http://linked.open...n/vavai/riv/zamer
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number of pages
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http://purl.org/ne...btex#hasPublisher
| - Masarykova univerzita. Lékařská fakulta
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http://localhost/t...ganizacniJednotka
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