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  • The aim of this study was to examine the effect of sigma receptor ligand haloperidol in guinea pig atrial preparations. Stimulated contractions were recorded and analysed by time- and time-frequency methods. The analysis revealed that the compound exerts marked positive inotropic effect. This was significantly less pronounced in case of repeated drug administration. We conclude that sigma receptors in guinea pig atria undergo a desensitization process.
  • The aim of this study was to examine the effect of sigma receptor ligand haloperidol in guinea pig atrial preparations. Stimulated contractions were recorded and analysed by time- and time-frequency methods. The analysis revealed that the compound exerts marked positive inotropic effect. This was significantly less pronounced in case of repeated drug administration. We conclude that sigma receptors in guinea pig atria undergo a desensitization process. (en)
  • The aim of this study was to examine the effect of sigma receptor ligand haloperidol in guinea pig atrial preparations. Stimulated contractions were recorded and analysed by time- and time-frequency methods. The analysis revealed that the compound exerts marked positive inotropic effect. This was significantly less pronounced in case of repeated drug administration. We conclude that sigma receptors in guinea pig atria undergo a desensitization process. (cs)
Title
  • Time- and Time-frequency analysis of Contractility and Desensitisation in Multicellular Heart Preparations
  • Time- and Time-frequency analysis of Contractility and Desensitisation in Multicellular Heart Preparations (en)
  • Time- and Time-Frequency Analysis of Contractility and Desensitisation in Multicellular Heart Preparations (cs)
skos:prefLabel
  • Time- and Time-frequency analysis of Contractility and Desensitisation in Multicellular Heart Preparations
  • Time- and Time-frequency analysis of Contractility and Desensitisation in Multicellular Heart Preparations (en)
  • Time- and Time-Frequency Analysis of Contractility and Desensitisation in Multicellular Heart Preparations (cs)
skos:notation
  • RIV/00216224:14110/02:00006875!RIV08-GA0-14110___
http://linked.open.../vavai/riv/strany
  • 554
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA102/01/1494)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 667020
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/02:00006875
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • cardiac contractility; side effects of neuroleptics; sigma receptor; wavelet analysis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [0BE2D81C1C1E]
http://linked.open...v/mistoKonaniAkce
  • Vienna, 4.-8.12.2002
http://linked.open...i/riv/mistoVydani
  • Vienna
http://linked.open...i/riv/nazevZdroje
  • Proceedings of International Federation of Medical and Biological Engineering
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Provazník, Ivo
  • Nováková, Marie
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
number of pages
http://purl.org/ne...btex#hasPublisher
  • EMBEC 02
https://schema.org/isbn
  • 3-901351-62-0
http://localhost/t...ganizacniJednotka
  • 14110
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