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Description
  • Článek studuje Paroxetin a vztah mezi CYP2D6, metabolickým stavem a sexuální dysfunkcí (cs)
  • This article describes the incidence of sexual dysfunction in 30 patients subjected to long-term treatment by paroxetine in dependence on the P 450 CYP 2D6 isoenzyme metabolic status. Measured on the Arizona Sexual Experience Scale (ASEX; McGahuey, Delgado, & Gelenberg, 1999), the incidence of sexual dysfunction inpatients converted to CYP 2D6 poor metabolizers was markedly higher compared with patients who had no history of such conversion, a difference that reached the level of statistical significance. Our article discusses the incidence of sexual dysfunction in connection with reduced CYP 2D6 capacity.
  • This article describes the incidence of sexual dysfunction in 30 patients subjected to long-term treatment by paroxetine in dependence on the P 450 CYP 2D6 isoenzyme metabolic status. Measured on the Arizona Sexual Experience Scale (ASEX; McGahuey, Delgado, & Gelenberg, 1999), the incidence of sexual dysfunction inpatients converted to CYP 2D6 poor metabolizers was markedly higher compared with patients who had no history of such conversion, a difference that reached the level of statistical significance. Our article discusses the incidence of sexual dysfunction in connection with reduced CYP 2D6 capacity. (en)
Title
  • Paroxetin a vztah mezi CYP2D6, metabolickým stavem a sexuální dysfunkcí (cs)
  • Relationship Between CYP 2D6 Metabolic Status and Sexual Dysfunction in Paroxetine Treatment
  • Relationship Between CYP 2D6 Metabolic Status and Sexual Dysfunction in Paroxetine Treatment (en)
skos:prefLabel
  • Paroxetin a vztah mezi CYP2D6, metabolickým stavem a sexuální dysfunkcí (cs)
  • Relationship Between CYP 2D6 Metabolic Status and Sexual Dysfunction in Paroxetine Treatment
  • Relationship Between CYP 2D6 Metabolic Status and Sexual Dysfunction in Paroxetine Treatment (en)
skos:notation
  • RIV/00216224:14110/02:00006445!RIV09-MZ0-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NF6159), Z(MSM 141100001)
http://linked.open...iv/cisloPeriodika
  • 5
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 661994
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/02:00006445
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • sexual dysfunction; CYP2D6; paroxetine; poor metabolizer (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [DD909B804193]
http://linked.open...i/riv/nazevZdroje
  • Journal of Sex and Marital Therapy
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 28
http://linked.open...iv/tvurceVysledku
  • Žourková, Alexandra
  • McCaskey Hadašová, Eva
http://linked.open...ain/vavai/riv/wos
  • 000178446900009
http://linked.open...n/vavai/riv/zamer
issn
  • 0092-623X
number of pages
http://localhost/t...ganizacniJednotka
  • 14110
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