About: CYTOSKELETON IN THE CELL CYCLE OF CRYPTOCOCCUS NEOFORMANS AND THE EFFECTS OF CYTOSKELETAL INHIBITORS     Goto   Sponge   NotDistinct   Permalink

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Description
  • The objectives of the study were (i) to identify morphologically distinct stages in the cell division cycle of C. neoformans, (ii) to identify microtubular and actin components of the cytoskeleton and (iii) to investigate the effect of two cytoskeletal inhibitors, Cytochalasin D and methylbenzimidazol-2-yl carbamate (MBC), on cell proliferation and potential cell death. Both interphase and M-phase were found to be characterised each by three distinct morphological stages: mother cell, development of a sterigma-like protrusion and bud emergence, and nuclear migration into the bud and subsequent mitosis, postmitotic phase, cytokinesis and cell separation. F-actin (patches, cables and cytokinetic rings) was similar to the ascomycetous budding yeast; patches accumulated at the apex of the growing sterigma, in the bud and around the septum, but also were evenly distributed in mother cells. Cytoplasmic and spindle microtubules were similar to those in the ascomycetous fission yeast. Cytoplasmic microtubule
  • The objectives of the study were (i) to identify morphologically distinct stages in the cell division cycle of C. neoformans, (ii) to identify microtubular and actin components of the cytoskeleton and (iii) to investigate the effect of two cytoskeletal inhibitors, Cytochalasin D and methylbenzimidazol-2-yl carbamate (MBC), on cell proliferation and potential cell death. Both interphase and M-phase were found to be characterised each by three distinct morphological stages: mother cell, development of a sterigma-like protrusion and bud emergence, and nuclear migration into the bud and subsequent mitosis, postmitotic phase, cytokinesis and cell separation. F-actin (patches, cables and cytokinetic rings) was similar to the ascomycetous budding yeast; patches accumulated at the apex of the growing sterigma, in the bud and around the septum, but also were evenly distributed in mother cells. Cytoplasmic and spindle microtubules were similar to those in the ascomycetous fission yeast. Cytoplasmic microtubule (en)
Title
  • CYTOSKELETON IN THE CELL CYCLE OF CRYPTOCOCCUS NEOFORMANS AND THE EFFECTS OF CYTOSKELETAL INHIBITORS
  • CYTOSKELETON IN THE CELL CYCLE OF CRYPTOCOCCUS NEOFORMANS AND THE EFFECTS OF CYTOSKELETAL INHIBITORS (en)
skos:prefLabel
  • CYTOSKELETON IN THE CELL CYCLE OF CRYPTOCOCCUS NEOFORMANS AND THE EFFECTS OF CYTOSKELETAL INHIBITORS
  • CYTOSKELETON IN THE CELL CYCLE OF CRYPTOCOCCUS NEOFORMANS AND THE EFFECTS OF CYTOSKELETAL INHIBITORS (en)
skos:notation
  • RIV/00216224:14110/01:00004338!RIV/2002/GA0/141102/N
http://linked.open.../vavai/riv/strany
  • 18-18
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA310/00/0391)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 676756
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/01:00004338
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • CYTOSKELETON IN THE CELL CYCLE OF CRYPTOCOCCUS NEOFORMANS AND THE EFFECTS OF CYTOSKELETAL INHIBITORS (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [3795A2B21D35]
http://linked.open...v/mistoKonaniAkce
  • Bratislava
http://linked.open...i/riv/mistoVydani
  • Bratislava
http://linked.open...i/riv/nazevZdroje
  • XXIX.Výrocná konferencia o kvasinkách, Kongresové centrum SAV Smolenice
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...ocetUcastnikuAkce
http://linked.open...nichUcastnikuAkce
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Kopecká, Marie
  • Yamaguchi, Masashi
  • Svoboda, Augustin
  • Gabriel, Miroslav
  • Takeo, Kanji
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
number of pages
http://purl.org/ne...btex#hasPublisher
  • Chemický ústav SAV
http://localhost/t...ganizacniJednotka
  • 14110
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