About: Cytoskeleton and morphological aberrations of septum formation and cytokinesis in cps6 mutant of Schizosaccharomyces pombe

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About: Cytoskeleton and morphological aberrations of septum formation and cytokinesis in cps6 mutant of Schizosaccharomyces pombe Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Cps6 mutant of the fission yeast is defective in cytokinesis, resulting in the formation of multiseptated cells.It is also more sensitive to digesting reagents than the wild type cells, suggesting that the mutant wall is altered in its composition or organization. The aim of this work was to examine wall and septum organization at the ultrastructural level and reinvestigate cytoskeleton in relation to aberrant phenotype.The results showed that the wall was less compact and more spongy with predominance of microfibrillar component.Lateral wall and septa were thicker. Septa remained unseparated.Cytoskeleton was well developed. Cps6 mutation may interfere with the termination of the synthesis of lateral wall and septum. Gene rad25+ coding for one of 14--3-3 homologs that complements cps6 mutation may be involved in pathway of cell wall integrity and proliferation. Cps6 mutant of the fission yeast is defective in cytokinesis, resulting in the formation of multiseptated cells.It is also more sensitive to digesting reagents than the wild type cells, suggesting that the mutant wall is altered in its composition or organization. The aim of this work was to examine wall and septum organization at the ultrastructural level and reinvestigate cytoskeleton in relation to aberrant phenotype.The results showed that the wall was less compact and more spongy with predominance of microfibrillar component.Lateral wall and septa were thicker. Septa remained unseparated.Cytoskeleton was well developed. Cps6 mutation may interfere with the termination of the synthesis of lateral wall and septum. Gene rad25+ coding for one of 14--3-3 homologs that complements cps6 mutation may be involved in pathway of cell wall integrity and proliferation. (en)
Title	Cytoskeleton and morphological aberrations of septum formation and cytokinesis in cps6 mutant of Schizosaccharomyces pombe Cytoskeleton and morphological aberrations of septum formation and cytokinesis in cps6 mutant of Schizosaccharomyces pombe (en)
skos:prefLabel	Cytoskeleton and morphological aberrations of septum formation and cytokinesis in cps6 mutant of Schizosaccharomyces pombe Cytoskeleton and morphological aberrations of septum formation and cytokinesis in cps6 mutant of Schizosaccharomyces pombe (en)
skos:notation	RIV/00216224:14110/00:00003572!RIV/2002/GA0/141102/N
http://linked.open.../vavai/riv/strany	11-11
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GA204/00/0394), P(GA310/00/0391)
http://linked.open...vai/riv/dodaniDat	2002
http://linked.open...aciTvurceVysledku	Gabriel, Miroslav Kopecká, Marie
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	707907
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/00:00003572
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	fission yeast, cytoskeleton, ultrastructure, cps mutant (en)
http://linked.open.../riv/klicoveSlovo	ultrastructure cytoskeleton fission yeast cps mutant
http://linked.open...ontrolniKodProRIV	[60F25E1BD349]
http://linked.open...v/mistoKonaniAkce	Praha
http://linked.open...i/riv/mistoVydani	Praha
http://linked.open...i/riv/nazevZdroje	VII. Cytoskeletální klub
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	The yeast cell wall as an extracellular matrix: cytoskeleton and cell wall functions Cytoskeleton in human pathogenic yeast microorganisms
http://linked.open...UplatneniVysledku	2000
http://linked.open...iv/tvurceVysledku	Kopecká, Marie Gabriel, Miroslav Ishiguro, Junpei
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2000-01-01 (xsd:date)
number of pages	1 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Ústav molekulární genetiky AV ČR
http://localhost/t...ganizacniJednotka	14110

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