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| rdf:type
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| rdfs:seeAlso
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| Description
| - To date, polymorphisms in several genes have been associated with a strength/power performance including alpha 3 actinin, ciliary neurotrophic factor, vitamin D receptor, or angiotensin I converting enzyme, underlining the importance of genetic component of the multifactorial strength/power-related phenotypes. The single nucleotide variation in peroxisome proliferator-activated receptor alpha gene (PPARA) intron 7 G/C (rs4253778; g. 46630634G>C) has been repeatedly found to play a significant role in response to different types of physical activity. We investigated the effect of PPARA intron 7 G/C polymorphism specifically on anaerobic power output in a group of 77 elite male Czech ice hockey players (18-36 y). We determined the relative peak power per body weight (P-max.kg(-1)) and relative peak power per fat free mass (W.kg(-1) (FFM)) during the 30-second Wingate Test (WT30) on bicycle ergometer (Monark 894E Peak bike, MONARK, Sweden). All WT30s were performed during the hockey season. Overall genotype frequencies were 50.6% GG homozygotes, 40.3% CG heterozygotes, and 9.1% CC homozygotes. We found statistically significant differences in P-max.kg(-1) and marginally significant differences in P-max.kg(-1) FFM values in WT30 between carriers and non-carriers for C allele (14.6 +/- 0.2 vs. 13.9 +/- 0.3 W.kg(-1) and 15.8 +/- 0.2 vs. 15.2 +/- 0.3 W.kg(-1) (FFM), P = 0.036 and 0.12, respectively). Furthermore, P-max.kg(-1) (FFM) strongly positively correlated with the body weight only in individuals with GG genotypes (R = 0.55; p<0.001). Our results indicate that PPARA 7C carriers exhibited higher speed strength measures in WT30. We hypothesize that C allele carriers within the cohort of trained individuals may possess a metabolic advantage towards anaerobic metabolism.
- To date, polymorphisms in several genes have been associated with a strength/power performance including alpha 3 actinin, ciliary neurotrophic factor, vitamin D receptor, or angiotensin I converting enzyme, underlining the importance of genetic component of the multifactorial strength/power-related phenotypes. The single nucleotide variation in peroxisome proliferator-activated receptor alpha gene (PPARA) intron 7 G/C (rs4253778; g. 46630634G>C) has been repeatedly found to play a significant role in response to different types of physical activity. We investigated the effect of PPARA intron 7 G/C polymorphism specifically on anaerobic power output in a group of 77 elite male Czech ice hockey players (18-36 y). We determined the relative peak power per body weight (P-max.kg(-1)) and relative peak power per fat free mass (W.kg(-1) (FFM)) during the 30-second Wingate Test (WT30) on bicycle ergometer (Monark 894E Peak bike, MONARK, Sweden). All WT30s were performed during the hockey season. Overall genotype frequencies were 50.6% GG homozygotes, 40.3% CG heterozygotes, and 9.1% CC homozygotes. We found statistically significant differences in P-max.kg(-1) and marginally significant differences in P-max.kg(-1) FFM values in WT30 between carriers and non-carriers for C allele (14.6 +/- 0.2 vs. 13.9 +/- 0.3 W.kg(-1) and 15.8 +/- 0.2 vs. 15.2 +/- 0.3 W.kg(-1) (FFM), P = 0.036 and 0.12, respectively). Furthermore, P-max.kg(-1) (FFM) strongly positively correlated with the body weight only in individuals with GG genotypes (R = 0.55; p<0.001). Our results indicate that PPARA 7C carriers exhibited higher speed strength measures in WT30. We hypothesize that C allele carriers within the cohort of trained individuals may possess a metabolic advantage towards anaerobic metabolism. (en)
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| Title
| - PPARA Intron Polymorphism Associated with Power Performance in 30-s Anaerobic Wingate Test
- PPARA Intron Polymorphism Associated with Power Performance in 30-s Anaerobic Wingate Test (en)
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| skos:prefLabel
| - PPARA Intron Polymorphism Associated with Power Performance in 30-s Anaerobic Wingate Test
- PPARA Intron Polymorphism Associated with Power Performance in 30-s Anaerobic Wingate Test (en)
|
| skos:notation
| - RIV/00216208:11510/14:10281173!RIV15-MSM-11510___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11510/14:10281173
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| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - physiology; metabolism; men; women; gamma; ice hockey; muscle strength; tissue distribution; alpha gene variation; proliferator-activated receptor (en)
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| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| |
| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Pecha, Ondřej
- Šťastný, Petr
- Kohlíková, Eva
- Petr, Miroslav
- Šteffl, Michal
- Šeda, Ondřej
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| http://linked.open...ain/vavai/riv/wos
| |
| http://linked.open...n/vavai/riv/zamer
| |
| issn
| |
| number of pages
| |
| http://bibframe.org/vocab/doi
| - 10.1371/journal.pone.0107171
|
| http://localhost/t...ganizacniJednotka
| |
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