About: Sarcopenia - brief characteristics, etiology and possible therapy

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Sarcopenia is considered to be a geriatric syndrome with multifactorial etiology: mitochondrial dysfunction, replication defects in mitochondrial DNA that lead deficit in energy production and muscle fibre atrophy, changes in protein synthesis, imbalance between protein degradation and the ability of muscle fibre to new proteins synthesis, changes in secretion and plasmatic levels of hormones (growth hormone, androgens, insulin etc.), metabolic syndrome or imbalance in antioxidant system and many more (Buford, et al., 2010). We are still far from being able to fully understand the causes and characteristics of sarcopenia as well as to solve this problem. However, an appropriate lifestyle (movement activity) and appropriate diets (energy restriction) seem to be the most effective therapeutic approaches (Morley, et al., 2010). Sarcopenia is considered to be a geriatric syndrome with multifactorial etiology: mitochondrial dysfunction, replication defects in mitochondrial DNA that lead deficit in energy production and muscle fibre atrophy, changes in protein synthesis, imbalance between protein degradation and the ability of muscle fibre to new proteins synthesis, changes in secretion and plasmatic levels of hormones (growth hormone, androgens, insulin etc.), metabolic syndrome or imbalance in antioxidant system and many more (Buford, et al., 2010). We are still far from being able to fully understand the causes and characteristics of sarcopenia as well as to solve this problem. However, an appropriate lifestyle (movement activity) and appropriate diets (energy restriction) seem to be the most effective therapeutic approaches (Morley, et al., 2010). (en)
Title	Sarcopenia - brief characteristics, etiology and possible therapy Sarcopenia - brief characteristics, etiology and possible therapy (en)
skos:prefLabel	Sarcopenia - brief characteristics, etiology and possible therapy Sarcopenia - brief characteristics, etiology and possible therapy (en)
skos:notation	RIV/00216208:11510/12:10106567!RIV13-MSM-11510___
http://linked.open...avai/predkladatel	Fakulta tělesné výchovy a sportu
http://linked.open...avai/riv/aktivita	S Z
http://linked.open...avai/riv/aktivity	S, Z(MSM0021620864)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Kohlíková, Eva Petr, Miroslav Šteffl, Michal Ruda, Tomáš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Fakulta tělesné výchovy a sportu
http://linked.open...dnocenehoVysledku	166732
http://linked.open...ai/riv/idVysledku	RIV/00216208:11510/12:10106567
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	energetic restriction; physical activity; geriatric syndrome; sarcopenia (en)
http://linked.open.../riv/klicoveSlovo	physical activity geriatric syndrome sarcopenia energetic restriction
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[C55CADA4F932]
http://linked.open...i/riv/nazevZdroje	Acta Universitatis Carolinae. Kinanthropologica
http://linked.open...in/vavai/riv/obor	AK
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	47
http://linked.open...iv/tvurceVysledku	Kohlíková, Eva Petr, Miroslav Šteffl, Michal Ruda, Tomáš
http://linked.open...n/vavai/riv/zamer	Aktivní životní styl v biosociálním kontextu
issn	1212-1428
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	11510
is http://linked.open...avai/riv/vysledek of	Sarcopenia - brief characteristics, etiology and possible therapy

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