About: Structural comparison of lipophosphoglycan from Leishmania turanica and L. major, two species transmitted by Phlebotomus papatasi     Goto   Sponge   NotDistinct   Permalink

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Description
  • The lipophosphoglycan (LPG) of Leishmania major has a major role in the attachment to Phlebotomus papatasi midgut. Here, we investigated the comparative structural features of LPG of L. turanica, another species transmitted by P. papatasi. The mAb WIC 79.3, specific for terminal Gal(β1,3) side-chains, strongly reacted with L. turanica LPG. In contrast, L. turanica LPG was not recognized by arabinose-specific mAb 3F12. In conclusion, LPGs from L. major and L. turanica are similar, with the latter being less arabinosylated than L. major's. The high galactose content in L. turanica LPG is consistent with its predicted recognition by P. papatasi lectin PpGalec
  • The lipophosphoglycan (LPG) of Leishmania major has a major role in the attachment to Phlebotomus papatasi midgut. Here, we investigated the comparative structural features of LPG of L. turanica, another species transmitted by P. papatasi. The mAb WIC 79.3, specific for terminal Gal(β1,3) side-chains, strongly reacted with L. turanica LPG. In contrast, L. turanica LPG was not recognized by arabinose-specific mAb 3F12. In conclusion, LPGs from L. major and L. turanica are similar, with the latter being less arabinosylated than L. major's. The high galactose content in L. turanica LPG is consistent with its predicted recognition by P. papatasi lectin PpGalec (en)
Title
  • Structural comparison of lipophosphoglycan from Leishmania turanica and L. major, two species transmitted by Phlebotomus papatasi
  • Structural comparison of lipophosphoglycan from Leishmania turanica and L. major, two species transmitted by Phlebotomus papatasi (en)
skos:prefLabel
  • Structural comparison of lipophosphoglycan from Leishmania turanica and L. major, two species transmitted by Phlebotomus papatasi
  • Structural comparison of lipophosphoglycan from Leishmania turanica and L. major, two species transmitted by Phlebotomus papatasi (en)
skos:notation
  • RIV/00216208:11310/14:10285221!RIV15-MSM-11310___
http://linked.open...avai/riv/aktivita
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  • I
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  • 5
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  • 47851
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  • RIV/00216208:11310/14:10285221
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  • Phlebotomus papatasi; Sand fly-Leishmania interaction; LPG; Leishmania turanica (en)
http://linked.open.../riv/klicoveSlovo
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  • JP - Japonsko
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  • [5FCFAAF9944A]
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  • Parasitology International
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  • 63
http://linked.open...iv/tvurceVysledku
  • Volf, Petr
  • Myšková, Jitka
  • Nogueira, Paula M.
  • Soares, Rodrigo P.
  • Turco, Salvatore J.
http://linked.open...ain/vavai/riv/wos
  • 000340513800005
issn
  • 1383-5769
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.parint.2014.05.004
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  • 11310
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