Attributes | Values |
---|
rdf:type
| |
rdfs:seeAlso
| |
Description
| - A facile bottom-up approach for the synthesis of inorganic/organic bioconjugated nanoprobes based on iron oxide nanocubes as the core with a nanometric silica shell is demonstrated. Surface coating and functionalization protocols developed in this work offered good control over the shell thickness (840 nm) and enabled biovectorization of SiO2@Fe3O4 coreshell structures by covalent attachment of folic acid (FA) as a targeting unit for cellular uptake. The successful immobilization of folic acid was investigated both quantitatively (TGA, EA, XPS) and qualitatively (AT-IR, UVvis, zeta-potential). Additionally, the magnetic behavior of the nanocomposites was monitored after each functionalization step. Cell viability studies confirmed low cytotoxicity of FA@SiO2@Fe3O4 conjugates, which makes them promising nanoprobes for targeted internalization by cells and their imaging.
- A facile bottom-up approach for the synthesis of inorganic/organic bioconjugated nanoprobes based on iron oxide nanocubes as the core with a nanometric silica shell is demonstrated. Surface coating and functionalization protocols developed in this work offered good control over the shell thickness (840 nm) and enabled biovectorization of SiO2@Fe3O4 coreshell structures by covalent attachment of folic acid (FA) as a targeting unit for cellular uptake. The successful immobilization of folic acid was investigated both quantitatively (TGA, EA, XPS) and qualitatively (AT-IR, UVvis, zeta-potential). Additionally, the magnetic behavior of the nanocomposites was monitored after each functionalization step. Cell viability studies confirmed low cytotoxicity of FA@SiO2@Fe3O4 conjugates, which makes them promising nanoprobes for targeted internalization by cells and their imaging. (en)
|
Title
| - Bioconjugated Iron Oxide Nanocubes: Synthesis, Functionalization, and Vectorization
- Bioconjugated Iron Oxide Nanocubes: Synthesis, Functionalization, and Vectorization (en)
|
skos:prefLabel
| - Bioconjugated Iron Oxide Nanocubes: Synthesis, Functionalization, and Vectorization
- Bioconjugated Iron Oxide Nanocubes: Synthesis, Functionalization, and Vectorization (en)
|
skos:notation
| - RIV/00216208:11310/14:10281900!RIV15-MSM-11310___
|
http://linked.open...avai/riv/aktivita
| |
http://linked.open...avai/riv/aktivity
| |
http://linked.open...iv/cisloPeriodika
| |
http://linked.open...vai/riv/dodaniDat
| |
http://linked.open...aciTvurceVysledku
| |
http://linked.open.../riv/druhVysledku
| |
http://linked.open...iv/duvernostUdaju
| |
http://linked.open...titaPredkladatele
| |
http://linked.open...dnocenehoVysledku
| |
http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11310/14:10281900
|
http://linked.open...riv/jazykVysledku
| |
http://linked.open.../riv/klicovaSlova
| - cytotoxicity; folic acid; magnetic properties; core-shell particles; iron oxide-silica; bioconjugated nanoprobes (en)
|
http://linked.open.../riv/klicoveSlovo
| |
http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
|
http://linked.open...ontrolniKodProRIV
| |
http://linked.open...i/riv/nazevZdroje
| - ACS applied materials & interfaces
|
http://linked.open...in/vavai/riv/obor
| |
http://linked.open...ichTvurcuVysledku
| |
http://linked.open...cetTvurcuVysledku
| |
http://linked.open...UplatneniVysledku
| |
http://linked.open...v/svazekPeriodika
| |
http://linked.open...iv/tvurceVysledku
| - Nižňanský, Daniel
- Mathur, Sanjay
- Arroub, Karim
- Berger, Nadja
- Holmes, Justin
- Ilyas, Shaista
- Rahme, Kamil
- Valldor, Martin
- Wortmann, Laura
|
http://linked.open...ain/vavai/riv/wos
| |
issn
| |
number of pages
| |
http://bibframe.org/vocab/doi
| |
http://localhost/t...ganizacniJednotka
| |