About: Seroprevalence Rates of BKV, JCV and MCPyV Polyomaviruses in the General Czech Republic Population

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About: Seroprevalence Rates of BKV, JCV and MCPyV Polyomaviruses in the General Czech Republic Population Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://onlinelibrary.wiley.com/doi/10.1002/jmv.23841/full
Description	JC and BK polyomaviruses (JCV and BKV) infect humans and can cause severe illnesses in immunocompromised patients. Merkel cell polyomavirus (MCPyV) can be found in skin carcinomas. In this study, we assessed the occurrence of serum antibodies against MCPyV, BKV, and JCV polyomaviruses in a healthy population of the Czech Republic. Serum samples from 991 healthy individuals (age range: 6-64 years) were examined by enzyme-linked immunoassay (ELISA) using virus-like particles (VLPs) based on the major VP1 capsid proteins of these viruses. Overall, serum antibodies against MCPyV, JCV, and BKV were found in 63%, 57%, and 69%, respectively, of this population. For all three viruses, these rates were associated with age; the occurrence of antibodies against MCPyV and JCV was highest for those older than 59 years, while the occurrence of antibodies against BKV was highest in those aged 10-19 years and 20-29 years. This is the first large study to determine the seroprevalence rates for BKV, JCV, and MCPyV polyomaviruses in the general Czech Republic population. J. Med. Virol. 9999: 1-9, 2013. (C) 2013 Wiley Periodicals, Inc. JC and BK polyomaviruses (JCV and BKV) infect humans and can cause severe illnesses in immunocompromised patients. Merkel cell polyomavirus (MCPyV) can be found in skin carcinomas. In this study, we assessed the occurrence of serum antibodies against MCPyV, BKV, and JCV polyomaviruses in a healthy population of the Czech Republic. Serum samples from 991 healthy individuals (age range: 6-64 years) were examined by enzyme-linked immunoassay (ELISA) using virus-like particles (VLPs) based on the major VP1 capsid proteins of these viruses. Overall, serum antibodies against MCPyV, JCV, and BKV were found in 63%, 57%, and 69%, respectively, of this population. For all three viruses, these rates were associated with age; the occurrence of antibodies against MCPyV and JCV was highest for those older than 59 years, while the occurrence of antibodies against BKV was highest in those aged 10-19 years and 20-29 years. This is the first large study to determine the seroprevalence rates for BKV, JCV, and MCPyV polyomaviruses in the general Czech Republic population. J. Med. Virol. 9999: 1-9, 2013. (C) 2013 Wiley Periodicals, Inc. (en)
Title	Seroprevalence Rates of BKV, JCV and MCPyV Polyomaviruses in the General Czech Republic Population Seroprevalence Rates of BKV, JCV and MCPyV Polyomaviruses in the General Czech Republic Population (en)
skos:prefLabel	Seroprevalence Rates of BKV, JCV and MCPyV Polyomaviruses in the General Czech Republic Population Seroprevalence Rates of BKV, JCV and MCPyV Polyomaviruses in the General Czech Republic Population (en)
skos:notation	RIV/00216208:11310/14:10191360!RIV15-MSM-11310___
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GAP304/10/1511)
http://linked.open...iv/cisloPeriodika	9
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Kojzarová, Martina Morávková, Alena Forstová, Jitka Fraiberk, Martin
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	44556
http://linked.open...ai/riv/idVysledku	RIV/00216208:11310/14:10191360
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	prevalence; polyomavirus; epidemiology; antibodies (en)
http://linked.open.../riv/klicoveSlovo	antibodies epidemiology prevalence polyomavirus
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[BCB3F012B674]
http://linked.open...i/riv/nazevZdroje	Journal of Medical Virology
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Study of the novel human polyomavirus (MCPyV) discovered in Merkel cell carcinomas.
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	86
http://linked.open...iv/tvurceVysledku	Němečková, Šárka Hamšíková, Eva Ludvíková, Viera Saláková, Martina Forstová, Jitka Fraiberk, Martin Morávková, Alena Šroller, Vojtěch Kojzarová, Martina Vochozková, Petra
http://linked.open...ain/vavai/riv/wos	000339486600014
issn	0146-6615
number of pages	9 (xsd:int)
http://bibframe.org/vocab/doi	10.1002/jmv.23841
http://localhost/t...ganizacniJednotka	11310

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