About: Right-To-Left Ventricular Differences in the Expression of Mitochondrial Hexokinase and Phosphorylation of Akt

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About: Right-To-Left Ventricular Differences in the Expression of Mitochondrial Hexokinase and Phosphorylation of Akt Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The purpose of this study was to investigate expression and subcellular localization of both HK isoforms in left (LV) and right (RV) heart ventricles of adult male Wistar rats. Our results showed a significantly higher expression of both HK1 and HK2 at mRNA and protein levels in the RV compared to the LV. These results suggest that the RV has a higher activity of aerobic glycolytic metabolism and may be able to respond faster and more powerfully to stressful stimuli than the LV. The purpose of this study was to investigate expression and subcellular localization of both HK isoforms in left (LV) and right (RV) heart ventricles of adult male Wistar rats. Our results showed a significantly higher expression of both HK1 and HK2 at mRNA and protein levels in the RV compared to the LV. These results suggest that the RV has a higher activity of aerobic glycolytic metabolism and may be able to respond faster and more powerfully to stressful stimuli than the LV. (en)
Title	Right-To-Left Ventricular Differences in the Expression of Mitochondrial Hexokinase and Phosphorylation of Akt Right-To-Left Ventricular Differences in the Expression of Mitochondrial Hexokinase and Phosphorylation of Akt (en)
skos:prefLabel	Right-To-Left Ventricular Differences in the Expression of Mitochondrial Hexokinase and Phosphorylation of Akt Right-To-Left Ventricular Differences in the Expression of Mitochondrial Hexokinase and Phosphorylation of Akt (en)
skos:notation	RIV/00216208:11310/13:10134368!RIV14-MSM-11310___
http://linked.open...avai/predkladatel	Přírodovědecká fakulta
http://linked.open...avai/riv/aktivita	I P S Z
http://linked.open...avai/riv/aktivity	I, P(IAA601110908), P(IAAX01110901), S, Z(AV0Z50110509), Z(MSM0021620858)
http://linked.open...iv/cisloPeriodika	31
http://linked.open...vai/riv/dodaniDat	2014
http://linked.open...aciTvurceVysledku	Elsnicová, Barbara Kašparová, Dita Šebesta, Ondřej Žurmanová, Jitka Arnoštová, Petra Novotný, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	102959
http://linked.open...ai/riv/idVysledku	RIV/00216208:11310/13:10134368
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Mitochondria co-localization; Right ventricle; Left ventricle; Akt kinase; Hexokinase isoforms (en)
http://linked.open.../riv/klicoveSlovo	Akt kinase Hexokinase isoforms Left ventricle Mitochondria co-localization Right ventricle
http://linked.open...odStatuVydavatele	CH - Švýcarská konfederace
http://linked.open...ontrolniKodProRIV	[E4E0FD4E49DD]
http://linked.open...i/riv/nazevZdroje	Cellular Physiology and Biochemistry
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	The role of adrenergic signaling and oxidative stress in molecular mechanisms of cardioprotection induced by chronic hypoxia Gene expression and copy number variation in behaviourally important mammalian genes
http://linked.open...UplatneniVysledku	2013
http://linked.open...v/svazekPeriodika	2013
http://linked.open...iv/tvurceVysledku	Neckář, Jan Novotný, Jiří Kolář, František Kašparová, Dita Žurmanová, Jitka Elsnicová, Barbara Wasková-Arnoštová, Petra Šebesta, Ondřej
http://linked.open...n/vavai/riv/zamer	Výzkum molekulárních a buněčných základů fyziologických a patofyziologických procesů s cílem objasnit mechanismy vzniku závažných onemocnění člověka Signaling and cellular response mechanisms
issn	1015-8987
number of pages	14 (xsd:int)
http://bibframe.org/vocab/doi	10.1159/000343350
http://localhost/t...ganizacniJednotka	11310

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