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  • Phosphoproteomic analysis of Src-transformed fibroblasts. To better understand the cellular impact of deregulated Src kinase activity, we extensively applied a mass spectrometry shotgun phosphotyrosine (pTyr) proteomics strategy to obtain global pTyr profiles of Src-transformed mouse fibroblasts as well as their nontransformed counterparts. A total of 867 peptides representing 563 distinct pTyr sites on 374 different proteins were identified from the Src-transformed cells, while 514 peptides representing 275 pTyr sites on 167 proteins were identified from nontransformed cells.
  • Phosphoproteomic analysis of Src-transformed fibroblasts. To better understand the cellular impact of deregulated Src kinase activity, we extensively applied a mass spectrometry shotgun phosphotyrosine (pTyr) proteomics strategy to obtain global pTyr profiles of Src-transformed mouse fibroblasts as well as their nontransformed counterparts. A total of 867 peptides representing 563 distinct pTyr sites on 374 different proteins were identified from the Src-transformed cells, while 514 peptides representing 275 pTyr sites on 167 proteins were identified from nontransformed cells. (en)
Title
  • Global impact of oncogenic Src on a phosphotyrosine proteome
  • Global impact of oncogenic Src on a phosphotyrosine proteome (en)
skos:prefLabel
  • Global impact of oncogenic Src on a phosphotyrosine proteome
  • Global impact of oncogenic Src on a phosphotyrosine proteome (en)
skos:notation
  • RIV/00216208:11310/08:13049!RIV11-MSM-11310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V
http://linked.open...iv/cisloPeriodika
  • 8
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 369445
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11310/08:13049
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • transformation; Src; pTyr (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [A642A6CAF550]
http://linked.open...i/riv/nazevZdroje
  • JOURNAL OF PROTEOME RESEARCH
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 7
http://linked.open...iv/tvurceVysledku
  • Brábek, Jan
  • Hanks, Steven
  • Amanchy, Ramars
  • Chaerkady, Raghothama
  • Ham, Amy-Joan
  • Hill, Salisha
  • Li, Ming
  • Luo, Weifeng
  • Pandey, Akhilesh
  • Slebos, Robbert
http://linked.open...ain/vavai/riv/wos
  • 000258200400035
issn
  • 1535-3893
number of pages
http://localhost/t...ganizacniJednotka
  • 11310
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