About: The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N-2-oxide

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About: The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N-2-oxide Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Protinádorové léčivo elipticin tvoří kovalentní DNA adukty, prostřednictvím cytochromů P450, přes metabolismus na 13-hydroxyelipticin a N-2-oxid elipticinu (cs) The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N-2-oxide The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N-2-oxide (en)
Title	Protinádorové léčivo elipticin tvoří kovalentní DNA adukty, prostřednictvím cytochromů P450, přes metabolismus na 13-hydroxyelipticin a N-2-oxid elipticinu (cs) The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N-2-oxide The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N-2-oxide (en)
skos:prefLabel	Protinádorové léčivo elipticin tvoří kovalentní DNA adukty, prostřednictvím cytochromů P450, přes metabolismus na 13-hydroxyelipticin a N-2-oxid elipticinu (cs) The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N-2-oxide The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N-2-oxide (en)
skos:notation	RIV/00216208:11310/04:00000707!RIV/2005/GA0/113105/N
http://linked.open.../vavai/riv/strany	8374;8380
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA203/01/0996), Z(MSM 113100001)
http://linked.open...iv/cisloPeriodika	22
http://linked.open...vai/riv/dodaniDat	2005
http://linked.open...aciTvurceVysledku	Svášková, Dagmar Sejbal, Jan Hudeček, Jiří Stiborová, Marie Bořek Dohalská, Lucie Poljaková, Jitka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	554786
http://linked.open...ai/riv/idVysledku	RIV/00216208:11310/04:00000707
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	LIVER-MICROSOMES;ENZYMES;BINDING;ACTIVATION;DYNAMICS;ANALOGS;AGENTS;ENERGY;CELLS (en)
http://linked.open.../riv/klicoveSlovo	CELLS BINDING ACTIVATION DYNAMICS ENERGY ANALOGS ENZYMES AGENTS LIVER-MICROSOMES
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[69D6F11460E0]
http://linked.open...i/riv/nazevZdroje	CANCER RESEARCH
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Study of molecular mechanism of anticancer effect of a chemotherapeutic, ellipticine
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	64
http://linked.open...iv/tvurceVysledku	Hudeček, Jiří Stiborová, Marie Aimová, Dagmar Sejbal, Jan Poljakova, Jitka Borek-Dohalska, Lucie
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20113100001
issn	0008-5472
number of pages	7 (xsd:int)
http://localhost/t...ganizacniJednotka	11310

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