About: Zirconia-A stationary phase capable of the separation of polar markers of myocardial metabolism in hydrophilic interaction chromatography

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About: Zirconia-A stationary phase capable of the separation of polar markers of myocardial metabolism in hydrophilic interaction chromatography Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://onlinelibrary.wiley.com/doi/10.1002/jssc.201301330/full
Description	This study describes a first systematic investigation of the ability of ZrO2 to separate creatine, phosphocreatine, adenosine 5-monophosphate, adenosine 5-diphosphate, and adenosine 5-triphosphate and compares the results with those obtained on TiO2. All analytes showed a HILIC-like retention pattern and both stronger retention and better column performance in organic-rich mobile phases as compared to aqueous conditions.The effect of mobile phase pH and ionic strength was evaluated as well. The analysis of myocardial tissue demonstrated that all compounds were separated in this biological material and thus proved ZrO2 as a promising phase for analysis of biological samples. This study describes a first systematic investigation of the ability of ZrO2 to separate creatine, phosphocreatine, adenosine 5-monophosphate, adenosine 5-diphosphate, and adenosine 5-triphosphate and compares the results with those obtained on TiO2. All analytes showed a HILIC-like retention pattern and both stronger retention and better column performance in organic-rich mobile phases as compared to aqueous conditions.The effect of mobile phase pH and ionic strength was evaluated as well. The analysis of myocardial tissue demonstrated that all compounds were separated in this biological material and thus proved ZrO2 as a promising phase for analysis of biological samples. (en)
Title	Zirconia-A stationary phase capable of the separation of polar markers of myocardial metabolism in hydrophilic interaction chromatography Zirconia-A stationary phase capable of the separation of polar markers of myocardial metabolism in hydrophilic interaction chromatography (en)
skos:prefLabel	Zirconia-A stationary phase capable of the separation of polar markers of myocardial metabolism in hydrophilic interaction chromatography Zirconia-A stationary phase capable of the separation of polar markers of myocardial metabolism in hydrophilic interaction chromatography (en)
skos:notation	RIV/00216208:11160/14:10282245!RIV15-MSM-11160___
http://linked.open...avai/riv/aktivita	I S
http://linked.open...avai/riv/aktivity	I, S
http://linked.open...iv/cisloPeriodika	9-10
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Slaninová, Jitka Kovaříková, Petra Klimeš, Jiří Kučera, Radim Pasáková, Ivana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Farmaceutická fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	57382
http://linked.open...ai/riv/idVysledku	RIV/00216208:11160/14:10282245
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Zirconia; Titania; Nucleotides; Hydrophilic interaction chromatography; Creatine (en)
http://linked.open.../riv/klicoveSlovo	Nucleotides Zirconia Creatine Titania Hydrophilic interaction chromatography
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[BCCBF3E30A96]
http://linked.open...i/riv/nazevZdroje	Journal of Separation Science
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	37
http://linked.open...iv/tvurceVysledku	Klimeš, Jiří Kovaříková, Petra Kučera, Radim Pasáková-Vrbatová, Ivana Slaninová, Jitka
http://linked.open...ain/vavai/riv/wos	000335196500006
issn	1615-9306
number of pages	5 (xsd:int)
http://bibframe.org/vocab/doi	10.1002/jssc.201301330
http://localhost/t...ganizacniJednotka	11160

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