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Description
  • The study evaluates the micronized poloxamers L(mu)trol micro127 (poloxamer 407) and L(mu)trol micro 68 (poloxamer 188) as lubricants in combination with the dry binders microcrystalline cellulose and spray-dried lactose. Magnesium stearate was employed as the comparative lubricant. The parameters under study included energy for friction, plasticity, ejection force, tensile strength of tablets, and disintegration time of tablets. The factors of influence were the concentration of lubricants, compression force, and mixing parameters.
  • The study evaluates the micronized poloxamers L(mu)trol micro127 (poloxamer 407) and L(mu)trol micro 68 (poloxamer 188) as lubricants in combination with the dry binders microcrystalline cellulose and spray-dried lactose. Magnesium stearate was employed as the comparative lubricant. The parameters under study included energy for friction, plasticity, ejection force, tensile strength of tablets, and disintegration time of tablets. The factors of influence were the concentration of lubricants, compression force, and mixing parameters. (en)
Title
  • A study of micronized poloxamers as lubricants in direct compression of tablets
  • A study of micronized poloxamers as lubricants in direct compression of tablets (en)
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  • A study of micronized poloxamers as lubricants in direct compression of tablets
  • A study of micronized poloxamers as lubricants in direct compression of tablets (en)
skos:notation
  • RIV/00216208:11160/13:10144252!RIV14-MSM-11160___
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
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  • I
http://linked.open...iv/cisloPeriodika
  • 6
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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  • 59104
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  • RIV/00216208:11160/13:10144252
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • disintegration time of tablets; tensile strength of tablets; ejection force; energy profile of compression; microcrystalline cellulose; spray-dried lactose; lubricants; micrionized poloxamers (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • PL - Polská republika
http://linked.open...ontrolniKodProRIV
  • [AEA56D1ECFAE]
http://linked.open...i/riv/nazevZdroje
  • Acta Poloniae Pharmaceutica
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 70
http://linked.open...iv/tvurceVysledku
  • Mužíková, Jitka
  • Pekárek, Tomáš
  • Vyhlídalová, Barbora
issn
  • 0001-6837
number of pages
http://localhost/t...ganizacniJednotka
  • 11160
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