About: Anthracyclines and their metabolism in human liver microsomes and the participation of the new microsomal carbonyl reductase     Goto   Sponge   NotDistinct   Permalink

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Description
  • Biotransformation of doxorubicin, daunorubicin, and idarubicin in human liver microsomal fraction and by novel human liver microsomal carbonyl reductase was done. Results obtained for the biotransformation of anthracyclines in human liver microsomal fraction indicate that there are two possible pathways for their metabolism.
  • Biotransformation of doxorubicin, daunorubicin, and idarubicin in human liver microsomal fraction and by novel human liver microsomal carbonyl reductase was done. Results obtained for the biotransformation of anthracyclines in human liver microsomal fraction indicate that there are two possible pathways for their metabolism. (en)
Title
  • Anthracyclines and their metabolism in human liver microsomes and the participation of the new microsomal carbonyl reductase
  • Anthracyclines and their metabolism in human liver microsomes and the participation of the new microsomal carbonyl reductase (en)
skos:prefLabel
  • Anthracyclines and their metabolism in human liver microsomes and the participation of the new microsomal carbonyl reductase
  • Anthracyclines and their metabolism in human liver microsomes and the participation of the new microsomal carbonyl reductase (en)
skos:notation
  • RIV/00216208:11160/11:10100416!RIV12-MSM-11160___
http://linked.open...avai/predkladatel
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  • 1-3
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  • 186383
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  • RIV/00216208:11160/11:10100416
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  • Enzyme kinetics; Idarubicin; Daunorubicin; Doxorubicin; Anthracyclines; Carbonyl reduction; Microsomal fraction; Microsomes; Purification (en)
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  • NL - Nizozemsko
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  • [7F7FFAC25101]
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  • Chemico-Biological Interactions
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  • 191
http://linked.open...iv/tvurceVysledku
  • Skarka, Adam
  • Wsól, Vladimír
  • Škarydová, Lucie
  • Štambergová, Hana
http://linked.open...ain/vavai/riv/wos
  • 000291767200013
issn
  • 0009-2797
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.cbi.2010.12.016
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  • 11160
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