About: Simple automated generation of gradient elution conditions in sequential injection chromatography using monolithic column

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Simple automated generation of gradient elution conditions in sequential injection chromatography using monolithic column Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.sciencedirect.com/science/article/pii/S0039914011000622
Description	The paper deals with the concept of simple automated creation of gradient profile of the mobile phase for gradient-elution sequential injection chromatography (GE-SIC). The feasibility and merits of this concept are demonstrated on the separation and simultaneous assay of indomethacin as active principle and of its two degradation products (5-methoxy-2-methylindoleacetic acid and 4-chloro-benzoic acid) in a topical pharmaceutical formulation. The GE-SIC separation was performed with a FIAlab (R) 3000 SIC set-up (USA) equipped with an Onyx (TM) Monolithic C18 (25 mm x 4.6 mm, Phenomenex (R)) column, a six-port selection valve, a 5-mL syringe pump and a fiber-optics UV CCD detector. Ketoprofen was used as an internal standard (IS). The gradient elution was achieved by automated reproducible mixing of acetonitrile and aqueous 0.2% phosphoric acid in the holding coil of the SIC system. The paper deals with the concept of simple automated creation of gradient profile of the mobile phase for gradient-elution sequential injection chromatography (GE-SIC). The feasibility and merits of this concept are demonstrated on the separation and simultaneous assay of indomethacin as active principle and of its two degradation products (5-methoxy-2-methylindoleacetic acid and 4-chloro-benzoic acid) in a topical pharmaceutical formulation. The GE-SIC separation was performed with a FIAlab (R) 3000 SIC set-up (USA) equipped with an Onyx (TM) Monolithic C18 (25 mm x 4.6 mm, Phenomenex (R)) column, a six-port selection valve, a 5-mL syringe pump and a fiber-optics UV CCD detector. Ketoprofen was used as an internal standard (IS). The gradient elution was achieved by automated reproducible mixing of acetonitrile and aqueous 0.2% phosphoric acid in the holding coil of the SIC system. (en)
Title	Simple automated generation of gradient elution conditions in sequential injection chromatography using monolithic column Simple automated generation of gradient elution conditions in sequential injection chromatography using monolithic column (en)
skos:prefLabel	Simple automated generation of gradient elution conditions in sequential injection chromatography using monolithic column Simple automated generation of gradient elution conditions in sequential injection chromatography using monolithic column (en)
skos:notation	RIV/00216208:11160/11:10100196!RIV12-MSM-11160___
http://linked.open...avai/predkladatel	Farmaceutická fakulta v Hradci Králové
http://linked.open...avai/riv/aktivita	S Z
http://linked.open...avai/riv/aktivity	S, Z(MSM0021620822)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Chocholouš, Petr Sklenářová, Hana Solich, Petr Polášek, Miroslav Koblová, Petra
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Farmaceutická fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	229287
http://linked.open...ai/riv/idVysledku	RIV/00216208:11160/11:10100196
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	sequential injection chromatography; monolithic column; indomethacin; HPLC; gradient elution; degradation products (en)
http://linked.open.../riv/klicoveSlovo	monolithic column degradation products gradient elution sequential injection chromatography HPLC indomethacin
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[D5F836E346E9]
http://linked.open...i/riv/nazevZdroje	Talanta
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	84
http://linked.open...iv/tvurceVysledku	Sklenářová, Hana Solich, Petr Polášek, Miroslav Chocholouš, Petr Koblová, Petra
http://linked.open...ain/vavai/riv/wos	000292475600013
http://linked.open...n/vavai/riv/zamer	Research of new drug structures
issn	0039-9140
number of pages	5 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.talanta.2011.01.029
http://localhost/t...ganizacniJednotka	11160
is http://linked.open...avai/riv/vysledek of	Simple automated generation of gradient elution conditions in sequential injection chromatography using monolithic column Simple automated generation of gradient elution conditions in sequential injection chromatography using monolithic column

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software