About: An unprecedented rearrangement of salicylanilide derivatives: imidazolinone intermediate formation

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The preparation of new prodrug forms of anti-tuberculosis active salicylanilide esters with amino acids led to an unexpected rearrangement. The isolation and the structure determination of 2-(5-chloro-2-hydroxyphenyl)-3-(3-chlorophenyl)-5-substituted-3,5-dihydro-4H-imidazol-4-ones unambiguously confirm one of the two proposed reaction mechanisms. The preparation of new prodrug forms of anti-tuberculosis active salicylanilide esters with amino acids led to an unexpected rearrangement. The isolation and the structure determination of 2-(5-chloro-2-hydroxyphenyl)-3-(3-chlorophenyl)-5-substituted-3,5-dihydro-4H-imidazol-4-ones unambiguously confirm one of the two proposed reaction mechanisms. (en)
Title	An unprecedented rearrangement of salicylanilide derivatives: imidazolinone intermediate formation An unprecedented rearrangement of salicylanilide derivatives: imidazolinone intermediate formation (en)
skos:prefLabel	An unprecedented rearrangement of salicylanilide derivatives: imidazolinone intermediate formation An unprecedented rearrangement of salicylanilide derivatives: imidazolinone intermediate formation (en)
skos:notation	RIV/00216208:11160/10:00300503!RIV11-MZ0-11160___
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(NS10367), S, Z(MSM0021620822), Z(MSM0021627501)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Krátký, Martin Palát, Karel Vinšová, Jarmila Monreal Férriz, Juana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Farmaceutická fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	246281
http://linked.open...ai/riv/idVysledku	RIV/00216208:11160/10:00300503
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	rearrangement; salicylanilide esters; imidazolinone (en)
http://linked.open.../riv/klicoveSlovo	rearrangement imidazolinone salicylanilide esters
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[1F563AFB85CD]
http://linked.open...i/riv/nazevZdroje	Tetrahedron Letters
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Evaluation and development of new perspective antimycobacterial drugs and prodrugs active against multidrug resistant strains
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	51
http://linked.open...iv/tvurceVysledku	Krátký, Martin Palát, Karel Růžička, Aleš Vinšová, Jarmila Imramovský, Aleš Lyčka, Antonín Monreal Férriz, Juana
http://linked.open...ain/vavai/riv/wos	000274232200003
http://linked.open...n/vavai/riv/zamer	Aimed preparation of special compounds and materials and investigation of their physical and chemical properties and supramolecular structures Research of new drug structures
issn	0040-4039
number of pages	4 (xsd:int)
http://localhost/t...ganizacniJednotka	11160
is http://linked.open...avai/riv/vysledek of	An unprecedented rearrangement of salicylanilide derivatives: imidazolinone intermediate formation An unprecedented rearrangement of salicylanilide derivatives: imidazolinone intermediate formation An unprecedented rearrangement of salicylanilide derivatives: imidazolinone intermediate formation

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