About: Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron

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About: Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In this study, we have focused on the outcomes of the studies dealing with the evaluation of the relationship of the anthracycline cardiotoxicity, oxidative stress and free cellular iron. It was proposed that other mechanisms than the traditionally emphasized 'ROS and iron' hypothesis are involved in anthracycline-induced cardiotoxicity and that these alternative mechanisms may be better bases for designing approaches to achieve efficient and safe cardioprotection. In this study, we have focused on the outcomes of the studies dealing with the evaluation of the relationship of the anthracycline cardiotoxicity, oxidative stress and free cellular iron. It was proposed that other mechanisms than the traditionally emphasized 'ROS and iron' hypothesis are involved in anthracycline-induced cardiotoxicity and that these alternative mechanisms may be better bases for designing approaches to achieve efficient and safe cardioprotection. (en)
Title	Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron (en)
skos:prefLabel	Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron (en)
skos:notation	RIV/00216208:11160/09:00210120!RIV10-GA0-11160___
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(GA305/09/0416), S, Z(MSM0021620820)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Šimůnek, Tomáš Hrdina, Radomír
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Farmaceutická fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	303425
http://linked.open...ai/riv/idVysledku	RIV/00216208:11160/09:00210120
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	anthracycline cardiotoxicity; doxorubicin (adriamycin); daunorubicin (daunomycin); epirubicin; dexrazoxane (ICRF-187); oxidative stress; cellular iron metabolism (en)
http://linked.open.../riv/klicoveSlovo	anthracycline cardiotoxicity cellular iron metabolism daunorubicin (daunomycin) dexrazoxane (ICRF-187) doxorubicin (adriamycin) oxidative stress epirubicin
http://linked.open...odStatuVydavatele	PL - Polská republika
http://linked.open...ontrolniKodProRIV	[5AC16932F805]
http://linked.open...i/riv/nazevZdroje	Pharmacological Reports
http://linked.open...in/vavai/riv/obor	FR
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Myocardial damage induced by anticancer drugs and ischemia-reperfusion: new possibilities of pharmacological cardioprotection.
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	61
http://linked.open...iv/tvurceVysledku	Adamcová, Michaela Šimůnek, Tomáš Geršl, Vladimír Popelová, Olga Štěrba, Martin Hrdina, Radomír
http://linked.open...ain/vavai/riv/wos	000265672200018
http://linked.open...n/vavai/riv/zamer	The use of experimental and clinical models of metabolic processes, nutrition and pharmacotherapy for the advancement of knowledge, clinical practice and quality of life improvement
issn	1734-1140
number of pages	18 (xsd:int)
http://localhost/t...ganizacniJednotka	11160
is http://linked.open...avai/riv/vysledek of	Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron

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