About: Liquid chromatographic-electrospray mass spectrometric determination (LC-ESI-MS) of phase II metabolites of flobufen in rat liver microsomes

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About: Liquid chromatographic-electrospray mass spectrometric determination (LC-ESI-MS) of phase II metabolites of flobufen in rat liver microsomes - Chiral discrimination Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Významným eliminačním mechanismem pro flobufen je glukuronace parentní molekuly i jeho hlavního metabolitu M17203; v jaterních mikrosomech potkana byly nalezeny o-glukuronidy flobufenu, jehož enantiomers vykazovaly rozdílné enzymové kinetiky (cs) Glucuronidation of flobufen and its major metabolite M17203 has been implicated as an important mechanism of flobufen elimination; o-glucuronides were identified in rat liver microsomes and different enzyme kinetics for two enantiomers was found Glucuronidation of flobufen and its major metabolite M17203 has been implicated as an important mechanism of flobufen elimination; o-glucuronides were identified in rat liver microsomes and different enzyme kinetics for two enantiomers was found (en)
Title	Liquid chromatographic-electrospray mass spectrometric determination (LC-ESI-MS) of phase II metabolites of flobufen in rat liver microsomes - Chiral discrimination LC-ESI-MS určení metabolitů flobufenu II. fáze v mikrosomech potkana - Chirální rozlišení (cs) Liquid chromatographic-electrospray mass spectrometric determination (LC-ESI-MS) of phase II metabolites of flobufen in rat liver microsomes - Chiral discrimination (en)
skos:prefLabel	Liquid chromatographic-electrospray mass spectrometric determination (LC-ESI-MS) of phase II metabolites of flobufen in rat liver microsomes - Chiral discrimination LC-ESI-MS určení metabolitů flobufenu II. fáze v mikrosomech potkana - Chirální rozlišení (cs) Liquid chromatographic-electrospray mass spectrometric determination (LC-ESI-MS) of phase II metabolites of flobufen in rat liver microsomes - Chiral discrimination (en)
skos:notation	RIV/00216208:11160/08:00109188!RIV09-MSM-11160___
http://linked.open...avai/riv/aktivita	S Z
http://linked.open...avai/riv/aktivity	S, Z(MSM0021620822)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2009
http://linked.open...aciTvurceVysledku	Wsól, Vladimír Solich, Petr Babú, Yogeeta
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Farmaceutická fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	376904
http://linked.open...ai/riv/idVysledku	RIV/00216208:11160/08:00109188
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	flobufen; chiral; enantiomers; LC-MS/MS; enzyme kinetics (en)
http://linked.open.../riv/klicoveSlovo	enzyme kinetics LC-MS/MS chiral flobufen enantiomers
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[E13AA350E7FC]
http://linked.open...i/riv/nazevZdroje	Talanta
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2008
http://linked.open...v/svazekPeriodika	75
http://linked.open...iv/tvurceVysledku	Němec, Michal Solich, Petr Wsól, Vladimír Babú, Yogeeta
http://linked.open...ain/vavai/riv/wos	000255270700026
http://linked.open...n/vavai/riv/zamer	Research of new drug structures
issn	0039-9140
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	11160
is http://linked.open...avai/riv/vysledek of	Liquid chromatographic-electrospray mass spectrometric determination (LC-ESI-MS) of phase II metabolites of flobufen in rat liver microsomes - Chiral discrimination Liquid chromatographic-electrospray mass spectrometric determination (LC-ESI-MS) of phase II metabolites of flobufen in rat liver microsomes - Chiral discrimination Liquid chromatographic-electrospray mass spectrometric determination (LC-ESI-MS) of phase II metabolites of flobufen in rat liver microsomes - Chiral discrimination Liquid chromatographic-electrospray mass spectrometric determination (LC-ESI-MS) of phase II metabolites of flobufen in rat liver microsomes - Chiral discrimination

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