About: Long-Term Outcomes of Rheohaemapheresis in the Treatment of Dry Form of Age-Related Macular Degeneration     Goto   Sponge   NotDistinct   Permalink

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  • Purpose. Determining long-term effects of rheohaemapheresis on the dry form of age-related macular degeneration. Methods. This study evaluates 19 patients, average age of 67.6 years, treated with rheohaemapheresis and 18 patients, average age of 72.8 years, comprising the control group. Minimum follow up period was 3.5 years. Each treated patient received a series of 8 sessions of rheohaemapheresis of 1.5 plasma volumes within 10 weeks. We measured the drusenoid pigment epithelium detachment (DPED), best-corrected visual acuity (BCVA), electroretinography (ERG), and rheological parameters. Results. In the treatment group, the baseline BCVA was 0.74 (0.36-1.0) 95% CI and BCVA after 3.5 years was 0.79 (0.41-1.0) 95% CI ( ). In the control group, the baseline BCVA was 0.71 (0.15-1.0) 95% CI and BCVA after 3.5 years decreased to 0.7 (0.32-0.87) 95% CI ( ). Baseline DPED was 6.78 +- 3.79 mm2; after 3.5 years, it decreased to 4.13 +- 3.84 mm2 ( ). In the control group, the baseline DPED was 4.09 +- 3.48 mm2; after 3.5 years, it increased to 6.69 +- 4.2 mm2 ( ). We noted increasing levels of positive wave peaking at 50 milliseconds (P50) after treatment ( ) and a stable amplitude of photopic responses of treated patients. Conclusion. Over the long term, rheohaemapheresis reduced the DPED, improved the function of photoreceptors, and prevented the decline of BCVA.
  • Purpose. Determining long-term effects of rheohaemapheresis on the dry form of age-related macular degeneration. Methods. This study evaluates 19 patients, average age of 67.6 years, treated with rheohaemapheresis and 18 patients, average age of 72.8 years, comprising the control group. Minimum follow up period was 3.5 years. Each treated patient received a series of 8 sessions of rheohaemapheresis of 1.5 plasma volumes within 10 weeks. We measured the drusenoid pigment epithelium detachment (DPED), best-corrected visual acuity (BCVA), electroretinography (ERG), and rheological parameters. Results. In the treatment group, the baseline BCVA was 0.74 (0.36-1.0) 95% CI and BCVA after 3.5 years was 0.79 (0.41-1.0) 95% CI ( ). In the control group, the baseline BCVA was 0.71 (0.15-1.0) 95% CI and BCVA after 3.5 years decreased to 0.7 (0.32-0.87) 95% CI ( ). Baseline DPED was 6.78 +- 3.79 mm2; after 3.5 years, it decreased to 4.13 +- 3.84 mm2 ( ). In the control group, the baseline DPED was 4.09 +- 3.48 mm2; after 3.5 years, it increased to 6.69 +- 4.2 mm2 ( ). We noted increasing levels of positive wave peaking at 50 milliseconds (P50) after treatment ( ) and a stable amplitude of photopic responses of treated patients. Conclusion. Over the long term, rheohaemapheresis reduced the DPED, improved the function of photoreceptors, and prevented the decline of BCVA. (en)
Title
  • Long-Term Outcomes of Rheohaemapheresis in the Treatment of Dry Form of Age-Related Macular Degeneration
  • Long-Term Outcomes of Rheohaemapheresis in the Treatment of Dry Form of Age-Related Macular Degeneration (en)
skos:prefLabel
  • Long-Term Outcomes of Rheohaemapheresis in the Treatment of Dry Form of Age-Related Macular Degeneration
  • Long-Term Outcomes of Rheohaemapheresis in the Treatment of Dry Form of Age-Related Macular Degeneration (en)
skos:notation
  • RIV/00216208:11150/13:10192011!RIV14-MZ0-11150___
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NT14037), V
http://linked.open...iv/cisloPeriodika
  • December
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 85406
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11150/13:10192011
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • drusenoid pigment epithelium detachment; visual acuity; age-related macular degeneration; rheohaemapheresis (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [315C4BC66C60]
http://linked.open...i/riv/nazevZdroje
  • Journal of Ophthalmology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • Neuveden
http://linked.open...iv/tvurceVysledku
  • Bláha, Milan
  • Rozsíval, Pavel
  • Lánská, Miriam
  • Bláha, Vladimír
  • Langrová, Hana
  • Rencová, Eva
  • Studnička, Jan
  • Němčanský, Jan
http://linked.open...ain/vavai/riv/wos
  • 000328970300001
issn
  • 2090-004X
number of pages
http://bibframe.org/vocab/doi
  • 10.1155/2013/135798
http://localhost/t...ganizacniJednotka
  • 11150
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