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| - The effect of lower doses (0.5-3.0 Gy) of gamma radiation on radiosensitivity of CD3-/CD8+ NK cells subpopulation isolated from the peripheral blood of healthy volunteers was studied 48 h after the irradiation. Only a subtle increase in terms of induction of apoptosis (A+cells), was observed in Annexin positive CD3-/CD8+ NK cells. The assessment of the relative presence of CD3-/CD8+ NK cells in Annexin negative populations of lymphocytes considerably contributes to the elimination of individual variability and could be useful in biodosimetry. Living CD3-/CD8+; Annexin negative NK cells were analyzed using five-color flow cytometry 16 hours after irradiation by the doses of 1-10 Gy. The study was carried out on NK cells subsets CD3-/CD8 - CD16+, CD56(dim) and CD56(bright). NK cells characterized with their low-density expression of CD56(dim) are more cytotoxic and express CD16.
- The effect of lower doses (0.5-3.0 Gy) of gamma radiation on radiosensitivity of CD3-/CD8+ NK cells subpopulation isolated from the peripheral blood of healthy volunteers was studied 48 h after the irradiation. Only a subtle increase in terms of induction of apoptosis (A+cells), was observed in Annexin positive CD3-/CD8+ NK cells. The assessment of the relative presence of CD3-/CD8+ NK cells in Annexin negative populations of lymphocytes considerably contributes to the elimination of individual variability and could be useful in biodosimetry. Living CD3-/CD8+; Annexin negative NK cells were analyzed using five-color flow cytometry 16 hours after irradiation by the doses of 1-10 Gy. The study was carried out on NK cells subsets CD3-/CD8 - CD16+, CD56(dim) and CD56(bright). NK cells characterized with their low-density expression of CD56(dim) are more cytotoxic and express CD16. (en)
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Title
| - Radiosensitivity of CD3-CD8+CD56+ NK cells
- Radiosensitivity of CD3-CD8+CD56+ NK cells (en)
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skos:prefLabel
| - Radiosensitivity of CD3-CD8+CD56+ NK cells
- Radiosensitivity of CD3-CD8+CD56+ NK cells (en)
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skos:notation
| - RIV/00216208:11150/10:10081136!RIV11-MO0-11150___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(OVUOFVZ200806), V, Z(MSM0021620820)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11150/10:10081136
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - aptosis; CD16; CD56bright NK cells; Ionizing radiation; Biodosimetry; NK cells (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Bláha, Václav
- Stoklasová, Alena
- Vávrová, Jiřina
- Vokurková, Doris
- Řezáčová, Martina
- Šinkora, Jiří
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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