About: Atypical Lipomatous Tumors of the Tongue: Report of Six Cases

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The occurence of liposarcoma (LS) in the tongue is rare with only 34 cases published so far. We report six new cases of atypical lipomatous tumor (ALT) of the tongue, and detection of mdm-2 and CDK4 expression by immunohistochemistry and fluorescence in situ hybridization (FISH) respectively was performed. To the best of our knowledge, this is the third largest series reporting ocurrence of ALT in the tongue and the first one, where analysis of mdm-2 and CDK4 proteins/genes expression/amplification was performed. Both these markers may be of help in the differential diagnosis of ALT versus lipoma. Although most ALTs of the tongue behave in the non-aggressive fashion, they may recur locally. Based on current data, the term ALT is strongly recommended for tumors occuring in the tongue to prevent inadequate treatment. The occurence of liposarcoma (LS) in the tongue is rare with only 34 cases published so far. We report six new cases of atypical lipomatous tumor (ALT) of the tongue, and detection of mdm-2 and CDK4 expression by immunohistochemistry and fluorescence in situ hybridization (FISH) respectively was performed. To the best of our knowledge, this is the third largest series reporting ocurrence of ALT in the tongue and the first one, where analysis of mdm-2 and CDK4 proteins/genes expression/amplification was performed. Both these markers may be of help in the differential diagnosis of ALT versus lipoma. Although most ALTs of the tongue behave in the non-aggressive fashion, they may recur locally. Based on current data, the term ALT is strongly recommended for tumors occuring in the tongue to prevent inadequate treatment. (en)
Title	Atypical Lipomatous Tumors of the Tongue: Report of Six Cases Atypical Lipomatous Tumors of the Tongue: Report of Six Cases (en)
skos:prefLabel	Atypical Lipomatous Tumors of the Tongue: Report of Six Cases Atypical Lipomatous Tumors of the Tongue: Report of Six Cases (en)
skos:notation	RIV/00216208:11150/09:00208523!RIV10-MZ0-11150___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MZ0FNHK2005)
http://linked.open...iv/cisloPeriodika	6
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Jiroušek, Zdeněk Ryška, Aleš Laco, Jan Hornychová, Helena Kohout, Aleš
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	304372
http://linked.open...ai/riv/idVysledku	RIV/00216208:11150/09:00208523
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	atypical lipomarous tumor; well differentiated liposarcoma; tongue; oral cavity; head and neck (en)
http://linked.open.../riv/klicoveSlovo	tongue oral cavity atypical lipomarous tumor well differentiated liposarcoma head and neck
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[CF288F98CAF2]
http://linked.open...i/riv/nazevZdroje	Virchows Archiv
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	455
http://linked.open...iv/tvurceVysledku	Hornychová, Helena Laco, Jan Ryška, Aleš Kohout, Aleš Jiroušek, Zdeněk Mentzel, Thomas
http://linked.open...ain/vavai/riv/wos	000271203300009
http://linked.open...n/vavai/riv/zamer	Nové diagnostické indikátory a léčebné postupy v závislosti na různých obdobích života s důrazem na stáří
issn	0945-6317
number of pages	6 (xsd:int)
http://localhost/t...ganizacniJednotka	11150
is http://linked.open...avai/riv/vysledek of	Atypical Lipomatous Tumors of the Tongue: Report of Six Cases Atypical Lipomatous Tumors of the Tongue: Report of Six Cases Atypical Lipomatous Tumors of the Tongue: Report of Six Cases Atypical Lipomatous Tumors of the Tongue: Report of Six Cases

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