About: Growth Hormone Treatment during Hemodialysis in a Randomized Trial Improves Nutrition, Quality of Life and Cardiovacular Risk

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The aim of this study was to establish clinical proof of concept of hGH treatment for the improvement of the nutritional status in adult patients who are on maintenance hemodialysis. Change in LBM and serum albumin (primary outcomes), health-related quality of life, and secondary efficacy and safety parameters were monitored. There were no differences in clinically relevant adverse events between groups. In conclusion, hGH therapy safely improves LBM, other markers of mortality and morbidity, and health-related quality of life in adult patients who are on maintenance hemodialysis. The aim of this study was to establish clinical proof of concept of hGH treatment for the improvement of the nutritional status in adult patients who are on maintenance hemodialysis. Change in LBM and serum albumin (primary outcomes), health-related quality of life, and secondary efficacy and safety parameters were monitored. There were no differences in clinically relevant adverse events between groups. In conclusion, hGH therapy safely improves LBM, other markers of mortality and morbidity, and health-related quality of life in adult patients who are on maintenance hemodialysis. (en) Cílem této studie bylo poskytnout klinický důkaz o konceptu léčby růstovým hormonem (hGH) pro zlepšení nutričního stavu dospělých pacientů na hemodialýze. Studie prokázala, že hGH ve všech koncentracích zvyšoval LBM, sérový albumin, transferin a HDL zatímco plazmatický homocystein a TNF-alfa se snižoval. Byla také pozorována zlepšená podškála the role physical SF-36 quality of life. Nebyly pozorovány rozdíly v klinicky relevantních nežádoucích účincích mezi skupinami. Závěrem lze říci, že léčba hGH bezpečně zlepšuje LBM a ostatní ukazatele morbidity a mortality u pacientů, kteří jsou na udržovací hemodialýze. (cs)
Title	Growth Hormone Treatment during Hemodialysis in a Randomized Trial Improves Nutrition, Quality of Life and Cardiovacular Risk Growth Hormone Treatment during Hemodialysis in a Randomized Trial Improves Nutrition, Quality of Life and Cardiovacular Risk (en) Léčba růstovým hormonem během dialýzy jako pokus o zlepšení nutrice, kvality života a kardiovaskulárního rizika (cs)
skos:prefLabel	Growth Hormone Treatment during Hemodialysis in a Randomized Trial Improves Nutrition, Quality of Life and Cardiovacular Risk Growth Hormone Treatment during Hemodialysis in a Randomized Trial Improves Nutrition, Quality of Life and Cardiovacular Risk (en) Léčba růstovým hormonem během dialýzy jako pokus o zlepšení nutrice, kvality života a kardiovaskulárního rizika (cs)
skos:notation	RIV/00216208:11150/07:00003948!RIV08-MSM-11150___
http://linked.open.../vavai/riv/strany	2161;2171
http://linked.open...avai/riv/aktivita	S
http://linked.open...avai/riv/aktivity	S
http://linked.open...iv/cisloPeriodika	7
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Dusilová - Sulková, Sylvie
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Hradci Králové
http://linked.open...dnocenehoVysledku	423692
http://linked.open...ai/riv/idVysledku	RIV/00216208:11150/07:00003948
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Growth; Hormone; Treatment; during; Hemodialysis; Randomized; Trial; Improves; Nutrition; Quality; Cardiovacular; Risk (en)
http://linked.open.../riv/klicoveSlovo	during Hormone Quality Risk Hemodialysis Treatment Growth Nutrition Randomized Improves Trial Cardiovacular
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[DF107640A24D]
http://linked.open...i/riv/nazevZdroje	Journal of the American Society of Nephrology
http://linked.open...in/vavai/riv/obor	FB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	23 (xsd:int)
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	18
http://linked.open...iv/tvurceVysledku	Dusilová-Sulková, Sylvie
issn	1046-6673
number of pages	11 (xsd:int)
http://localhost/t...ganizacniJednotka	11150
is http://linked.open...avai/riv/vysledek of	Growth Hormone Treatment during Hemodialysis in a Randomized Trial Improves Nutrition, Quality of Life and Cardiovacular Risk Growth Hormone Treatment during Hemodialysis in a Randomized Trial Improves Nutrition, Quality of Life and Cardiovacular Risk Growth Hormone Treatment during Hemodialysis in a Randomized Trial Improves Nutrition, Quality of Life and Cardiovacular Risk

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