About: The coexistence of well-differentiated neuroendocrine carcinoma (carcinoid) of the pancreas and Crohn´s disease complicated with systemic AA amyloidosis. A case report     Goto   Sponge   NotDistinct   Permalink

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  • We describe the case of 75-year-old male with Crohn’s disease (lasting 10 years, ileal and colon involvement) where multiple spheric nodules of well-differentiated neuroendocrine carcinoma (carcinoid) in liver parenchyma was proved in July 1999. Although there were both liver lobes involved, carcinoid syndrome occured five years after the diagnosis had been established. Therapy with lanreotide decreased the carcinoid symptoms, not the growth of the tumour mass. To find the origin of the liver metastases the patient underwent intra-operative enteroscopy with following resection of stenoses of distal ileum, ceacum and appendix in February 2005. We did not find the origin of carcinoid metastases of the liver during the patient’s life. Crohn’s disease was in full-remission the whole time. His health condition was serious and was complicated with bronchopneumonia, which led to death in November 2005.
  • We describe the case of 75-year-old male with Crohn’s disease (lasting 10 years, ileal and colon involvement) where multiple spheric nodules of well-differentiated neuroendocrine carcinoma (carcinoid) in liver parenchyma was proved in July 1999. Although there were both liver lobes involved, carcinoid syndrome occured five years after the diagnosis had been established. Therapy with lanreotide decreased the carcinoid symptoms, not the growth of the tumour mass. To find the origin of the liver metastases the patient underwent intra-operative enteroscopy with following resection of stenoses of distal ileum, ceacum and appendix in February 2005. We did not find the origin of carcinoid metastases of the liver during the patient’s life. Crohn’s disease was in full-remission the whole time. His health condition was serious and was complicated with bronchopneumonia, which led to death in November 2005. (en)
  • Kazuistika popisuje 75-letého muže s Crohnovou chorobou trvající 10 let s maximem postižení terminálního ilea a céka, u kterého byla v červnu 1999 prokázána vícečetná ložiska dobře diferencovaného neuroendokrinního karcinomu (karcinoidu) v jaterním parenchymu, bez znalosti primárního zdroje. Ačkoliv byly postiženy oba jaterní laloky, karcinoidový syndrom se objevil až po pěti letech od stanovení diagnózy. Léčba lanreotidem snížila příznaky, ale ne velikost nádorových ložisek v jaterním parenchymu. Pro stenózu terminálního ilea a ke zjištění eventuelního primárního zdroje karcinoidu pacient podstoupil v únoru 2005 intraoperační enteroskopii s následnou resekcí terminálního ilea, céka a apendixu. Při této operaci ani v průběhu následujícího období života pacienta jsme však primární zdroj metastáz karcinoidu do jater nenalezli. Crohnova choroba byla po celou dobu v remisi. Pacientův zdravotní stav byl vážný a byl komplikovaný bronchopneumonií, na kterou v listopadu 2005 nemocný zemřel. (cs)
Title
  • The coexistence of well-differentiated neuroendocrine carcinoma (carcinoid) of the pancreas and Crohn´s disease complicated with systemic AA amyloidosis. A case report
  • Současný výskyt diferencovaného endokrinního karcinomu (karcinoidu) pankreatu a Crohnovy choroby komplikované systémovou AA amyloidózou. Kasuistika (cs)
  • The coexistence of well-differentiated neuroendocrine carcinoma (carcinoid) of the pancreas and Crohn´s disease complicated with systemic AA amyloidosis. A case report (en)
skos:prefLabel
  • The coexistence of well-differentiated neuroendocrine carcinoma (carcinoid) of the pancreas and Crohn´s disease complicated with systemic AA amyloidosis. A case report
  • Současný výskyt diferencovaného endokrinního karcinomu (karcinoidu) pankreatu a Crohnovy choroby komplikované systémovou AA amyloidózou. Kasuistika (cs)
  • The coexistence of well-differentiated neuroendocrine carcinoma (carcinoid) of the pancreas and Crohn´s disease complicated with systemic AA amyloidosis. A case report (en)
skos:notation
  • RIV/00216208:11150/06:00005009!RIV08-MSM-11150___
http://linked.open.../vavai/riv/strany
  • 79;85
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • S
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 469030
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11150/06:00005009
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • coexistence; well-differentiated; neuroendocrine; carcinoma; carcinoid; pancreas; Crohn´s; disease; complicated; systemic; amyloidosis; report (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [D87524F9A352]
http://linked.open...i/riv/nazevZdroje
  • Folia Gastroenterologica et Hepatologica
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 4
http://linked.open...iv/tvurceVysledku
  • Bureš, Jan
  • Vižďa, Jaroslav
  • Kohout, Aleš
issn
  • 1214-4088
number of pages
http://localhost/t...ganizacniJednotka
  • 11150
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