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| rdf:type
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| Description
| - Cíl: cílem této studie bylo zhodnotit vliv orálně podávaného vitamínu E na sérové koncentrace několika markerů mikrozánětu a kardiovaskulární choroby u chronicky hemodialyzovaných (HD) pacientů. Výsledky: u pacientů s HD byly základní sérové hladiny PAPP-A a CRP signifikantně vyšší než u zdravých kontrol. Po 5 týdnech suplementace vitamínem E se sérové koncentrace všech vyšetřovaných markerů u pacientů s HD nezměnily. Závěr: chronický mikrozánět u pacientů s HD je spojen se zvýšením hladin CRP a PAPPA-A. Denní orální dávka 400 mg vitamínu E se zdá být neúčinná u pacientů s HD. (cs)
- The aim of this study was to evaluate the influence of oral vitamin E therapy on serum concentrations of several markers of micro-inflammation and cardiovascular disease in chronic hemodialysis (HD) patients. 29 HD patients were randomized into two groups: 15 patients were treated orally with 400mg of vitamin E daily for a period of five weeks, and 14 patients received no antioxidant supplementation. Before and after vitamin E therapy, serum concentrations of vitamin E (high-performance liquid chromatography), pregnancy-associated plasma protein-A (immunochemical - TRACE assay), C-reactive protein (nephelometry), intercellular adhesion molecule-1 (ELISA), and E-selectin (ELISA) were measured. HD patients were compared with 16 healthy controls. Conclusion. Chronic micro-inflammation in HD patients is documented by the elevation of CRP and PAPPA. A daily oral dose of 400 mg of vitamin E does not seem to be able to reduce enhanced oxidative stress and micro-inflammation in chronic HD patients.
- The aim of this study was to evaluate the influence of oral vitamin E therapy on serum concentrations of several markers of micro-inflammation and cardiovascular disease in chronic hemodialysis (HD) patients. 29 HD patients were randomized into two groups: 15 patients were treated orally with 400mg of vitamin E daily for a period of five weeks, and 14 patients received no antioxidant supplementation. Before and after vitamin E therapy, serum concentrations of vitamin E (high-performance liquid chromatography), pregnancy-associated plasma protein-A (immunochemical - TRACE assay), C-reactive protein (nephelometry), intercellular adhesion molecule-1 (ELISA), and E-selectin (ELISA) were measured. HD patients were compared with 16 healthy controls. Conclusion. Chronic micro-inflammation in HD patients is documented by the elevation of CRP and PAPPA. A daily oral dose of 400 mg of vitamin E does not seem to be able to reduce enhanced oxidative stress and micro-inflammation in chronic HD patients. (en)
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| Title
| - Influence of Oral Vitamin E Therapy on Micro-Inflammation and Cardiovascular Disease Markers in Chronic Hemodialysis Patients
- Influence of Oral Vitamin E Therapy on Micro-Inflammation and Cardiovascular Disease Markers in Chronic Hemodialysis Patients (en)
- Vliv perorální podávání vitaminu E na mikrozánět a markery kardiovakulárního poškození u chronicky hemodialyzovaných pacientů (cs)
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| skos:prefLabel
| - Influence of Oral Vitamin E Therapy on Micro-Inflammation and Cardiovascular Disease Markers in Chronic Hemodialysis Patients
- Influence of Oral Vitamin E Therapy on Micro-Inflammation and Cardiovascular Disease Markers in Chronic Hemodialysis Patients (en)
- Vliv perorální podávání vitaminu E na mikrozánět a markery kardiovakulárního poškození u chronicky hemodialyzovaných pacientů (cs)
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| skos:notation
| - RIV/00216208:11150/06:00004991!RIV08-MSM-11150___
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
| - P(NR8094), S, Z(MSM0021620812)
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11150/06:00004991
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Influence; Vitamin; Therapy; Micro-Inflammation; Cardiovascular; Disease; Markers; Chronic; Hemodialysis; Patients (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...vavai/riv/projekt
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
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| http://linked.open...n/vavai/riv/zamer
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| http://localhost/t...ganizacniJednotka
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| is http://linked.open...avai/riv/vysledek
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