| Attributes | Values |
|---|
| rdf:type
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| Description
| - Epitel gastrointestinálního traktu hraje důležitou roli nejen při trávení a absorpci živin, ale i při translokaci antigenů a patogenů směrem k se střevem asociované lymfoidní tkání. Malnutrice je nejčastější příčinou dysfunkce imunitního systému. V poslední době bylo zjištěno, že nukleotidy potravy (dNT) jsou esenciální složkou potravy během obnovy tkání. V předchozích pokusech jsme prokázali imunomodulační účinky extraktů obsahující dNT. V současné studii byly samičky myší Balb/c krmeny 4 týdny standardní dietou, dietou suplementovanou dNT (dávka 100 mg/kg/l) nebo vodou suplementovanou dNT. U zvířat, kterým byla podávána voda suplementovaná dTN byl pozorován největší růst střevních klků. Patologické změny střevního epitelu nebyly zjištěny v žádné pokusné skupině. (cs)
- The gastrointestinal tract epithelium plays an important role not only in digestion and absorption of nutrients, but also in antigen and pathogen signal translocation toward the gut associated lymphoid tissue. Malnutrition in various degrees is recognized as the most common cause of the immune system dysfunction. Research done in the past several years has revealed that dietary nucleotides (dNT) represent an essential compound of nutrition because of their importance in metabolic pathways, energetic processes and nucleic acid synthesis during tissue renewal. In previous experiments we have documented immunoregulative properties of dNT- containing extracts. In this study Balb/c female mice were fed (1) standard diet, (2) dNT-supplemented diet, and (3) dNT-supplemented water for 4 weeks. The highest growth of intestinal villi was observed in group administered dNT-supplemented water. We have found no pathological changes of intestinal epithelium in any experimental group.
- The gastrointestinal tract epithelium plays an important role not only in digestion and absorption of nutrients, but also in antigen and pathogen signal translocation toward the gut associated lymphoid tissue. Malnutrition in various degrees is recognized as the most common cause of the immune system dysfunction. Research done in the past several years has revealed that dietary nucleotides (dNT) represent an essential compound of nutrition because of their importance in metabolic pathways, energetic processes and nucleic acid synthesis during tissue renewal. In previous experiments we have documented immunoregulative properties of dNT- containing extracts. In this study Balb/c female mice were fed (1) standard diet, (2) dNT-supplemented diet, and (3) dNT-supplemented water for 4 weeks. The highest growth of intestinal villi was observed in group administered dNT-supplemented water. We have found no pathological changes of intestinal epithelium in any experimental group. (en)
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| Title
| - Stimulace růstu a regenerace epitelu ilea pomocí diety s nukleotidovými extrakty (cs)
- Stimulation of ileal epithelium growth and regeneration by dietary nucleotide extracts
- Stimulation of ileal epithelium growth and regeneration by dietary nucleotide extracts (en)
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| skos:prefLabel
| - Stimulace růstu a regenerace epitelu ilea pomocí diety s nukleotidovými extrakty (cs)
- Stimulation of ileal epithelium growth and regeneration by dietary nucleotide extracts
- Stimulation of ileal epithelium growth and regeneration by dietary nucleotide extracts (en)
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| skos:notation
| - RIV/00216208:11150/04:00004680!RIV08-MSM-11150___
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| http://linked.open.../vavai/riv/strany
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
| |
| http://linked.open...aciTvurceVysledku
| |
| http://linked.open.../riv/druhVysledku
| |
| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
| |
| http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11150/04:00004680
|
| http://linked.open...riv/jazykVysledku
| |
| http://linked.open.../riv/klicovaSlova
| - Stimulation; ileal; epithelium; growth; regeneration; dietary; nucleotide; extracts (en)
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| http://linked.open.../riv/klicoveSlovo
| |
| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
| - Acta Medica (Hradec Králové)
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| http://linked.open...in/vavai/riv/obor
| |
| http://linked.open...ichTvurcuVysledku
| |
| http://linked.open...cetTvurcuVysledku
| |
| http://linked.open...UplatneniVysledku
| |
| http://linked.open...v/svazekPeriodika
| |
| http://linked.open...iv/tvurceVysledku
| - Krs, Otakar
- Slížová, Dáša
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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