About: The 'edge effect' after implantation of beta-emitting (55CO) stents with high initial activity     Goto   Sponge   NotDistinct   Permalink

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Description
  • Cílem této studie bylo zhodnotit incidenci a příčinu 'okrajové restenózy' po implantaci vysoce aktivních beta-emitujících (55Co) stentů. Bombardování protony v cyklotronu spouští radioaktivitu. Vyšetření intravaskulárním ultrazvukem bylo dokončeno u 10 pacientů. Angiografie provedená po 6 měsících objevila restenózu > 50 % v 5 případech. Analýza okrajů neprokázala významné změny v TVV, ale PMV výrazně vzrostlo a bylo hlavním přispěvatelem ke ztrátě objemu lumen. Nebyla přítomna remodelace na okrajích stentu, avšak statisticky významný vzrůst objemu média a destičky (tj. neointimální proliferace) a pokles objemu lumen. Hlavním důvodem 'okrajového' efektu/neointimální hyperplazie byl zřejmě v tomto pokusu ostrý pokles radiace v okrajích stentu. (cs)
  • The aim of this study was to evaluate the incidence and the cause of 'edge' restenosis after implantation of high activity beta-emitting (55Co) stents. Proton bombarding in cyclotron has brought the radioactivity. Intravascular ultrasound investigation has been completed in 10 patients. The angiographies performed at 6 month revealed restenosis >50 % in 5 cases. In conclusion, neither statistically significant positive nor negative remodelling at the 'stent edges', were present. Statistically significant increase in plaque media volume (i.e. neointimal hyperplasia) and reduction in lumen volume were found. The cause of 'edge restenosis was especially due to increase in plaque+media volume (i.e. neointimal hyperplasia). Probably, main reason for 'edge effect'/neointimal hyperplasia was in this trial sharp fall-off in radiation at the edges of the stents.
  • The aim of this study was to evaluate the incidence and the cause of 'edge' restenosis after implantation of high activity beta-emitting (55Co) stents. Proton bombarding in cyclotron has brought the radioactivity. Intravascular ultrasound investigation has been completed in 10 patients. The angiographies performed at 6 month revealed restenosis >50 % in 5 cases. In conclusion, neither statistically significant positive nor negative remodelling at the 'stent edges', were present. Statistically significant increase in plaque media volume (i.e. neointimal hyperplasia) and reduction in lumen volume were found. The cause of 'edge restenosis was especially due to increase in plaque+media volume (i.e. neointimal hyperplasia). Probably, main reason for 'edge effect'/neointimal hyperplasia was in this trial sharp fall-off in radiation at the edges of the stents. (en)
Title
  • The 'edge effect' after implantation of beta-emitting (55CO) stents with high initial activity
  • The 'edge effect' after implantation of beta-emitting (55CO) stents with high initial activity (en)
  • 'Okrajový' efekt po implantaci beta-emitujících stentů (55Co) s vysokou iniciální aktivitou (cs)
skos:prefLabel
  • The 'edge effect' after implantation of beta-emitting (55CO) stents with high initial activity
  • The 'edge effect' after implantation of beta-emitting (55CO) stents with high initial activity (en)
  • 'Okrajový' efekt po implantaci beta-emitujících stentů (55Co) s vysokou iniciální aktivitou (cs)
skos:notation
  • RIV/00216208:11150/04:00004458!RIV08-MSM-11150___
http://linked.open.../vavai/riv/strany
  • 37;42
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NA4786), S
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 561669
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11150/04:00004458
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • 'edge; effect'; after; implantation; beta-emitting; stents; initial; activity (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [FFE4503A2DBD]
http://linked.open...i/riv/nazevZdroje
  • Acta Medica (Hradec Králové)
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 47
http://linked.open...iv/tvurceVysledku
  • Malý, Jaroslav
  • Pleskot, Miloslav
  • Šťásek, Josef
issn
  • 1211-4286
number of pages
http://localhost/t...ganizacniJednotka
  • 11150
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