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rdf:type
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Description
| - Úvod: fibrilace síní (AF) je nejčastějším typem klinicky pozorované arytmie. Myokardiální rukávce na plicních žílách (PV) jsou častým místem původu fokálních iniciátorů této arytmie. Existuje hypotéza, že exprese Leu-7 koresponduje s abnormální automaticitou srdečních síní. Cíl: zhodnotit možnou úlohu imunoreaktivity Leu-7 u pacientů s AF v jejich myokardiálních rukávcích. Závěry: Určitá pozitivita na Leu-7 se dá nalézt u některých myokardiálních rukávců okolo PV. Na druhé straně však nebyl nalezen žádný vztah mezi touto aktivitou a předchozí historií AF. (cs)
- Background: Atrial fibrillation (AF) is the most common sustained clinical arrhythmia. Myocardial sleeves onto pulmonary veins (PVs) have been recognized as a frequent site of origin of focal triggers for this arrhythmia. Expression of Leu-7 has been hypothesized to correspond with abnormal atrial automaticity. Objective: To evaluate a possible role of the Leu-7 immunoreactivity in AF patients, we studied Leu-7 expression in myocardial sleeves. Methods: Leu-7 was studied immunohistochemically in paraffin-embedded specimens from 55 human autopsied hearts (mean age 69 years, range 42-94 years, 34 males, 21 females). Twenty-two of the subjects had previous history of AF. Conclusions: Leu-7 positivity, hypothesized to correspond with abnormal atrial automaticity, can be detected in some myocardial sleeves around PVs. However, no statistical relationship to previous history of AF was found.
- Background: Atrial fibrillation (AF) is the most common sustained clinical arrhythmia. Myocardial sleeves onto pulmonary veins (PVs) have been recognized as a frequent site of origin of focal triggers for this arrhythmia. Expression of Leu-7 has been hypothesized to correspond with abnormal atrial automaticity. Objective: To evaluate a possible role of the Leu-7 immunoreactivity in AF patients, we studied Leu-7 expression in myocardial sleeves. Methods: Leu-7 was studied immunohistochemically in paraffin-embedded specimens from 55 human autopsied hearts (mean age 69 years, range 42-94 years, 34 males, 21 females). Twenty-two of the subjects had previous history of AF. Conclusions: Leu-7 positivity, hypothesized to correspond with abnormal atrial automaticity, can be detected in some myocardial sleeves around PVs. However, no statistical relationship to previous history of AF was found. (en)
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Title
| - Exprese Leu-7 v myokardiálních rukávcích okolo plicních žil člověka (cs)
- Expression of Leu-7 in myocardial sleeves around human pulmonary veins
- Expression of Leu-7 in myocardial sleeves around human pulmonary veins (en)
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skos:prefLabel
| - Exprese Leu-7 v myokardiálních rukávcích okolo plicních žil člověka (cs)
- Expression of Leu-7 in myocardial sleeves around human pulmonary veins
- Expression of Leu-7 in myocardial sleeves around human pulmonary veins (en)
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skos:notation
| - RIV/00216208:11150/03:00004228!RIV08-MSM-11150___
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11150/03:00004228
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Expression; Leu-7; myocardial; sleeves; around; human; pulmonary; veins (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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