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Description
  • Nodular mucinosis of the breast (NMB) is a rare entity with only a few cases described in the literature, most of them in young girls. All cases are located in the nipple and areolar area and microscopically consist of a multinodular myxoid mesenchymal proliferation. Bands of sclerotic collagen containing preexisting breast ducts and abundant vascularization are other features typical of NMB. No relation to Carney complex has been reported, and an indolent behavior is the rule in all patients. We present a case of NMB occurring in the nipple of a 46-year-old man and analyze the clinicopathological features of the other cases of NMB reported in the English literature, concluding that two of them most likely correspond to trauma- induced cutaneous focal mucinosis of the mammary areola. Finally, we review diagnostic criteria for NMB and elaborate an ontogenetic hypothesis based on both its morphological resemblance to myofibroblastoma and its immunohistochemical profile.
  • Nodular mucinosis of the breast (NMB) is a rare entity with only a few cases described in the literature, most of them in young girls. All cases are located in the nipple and areolar area and microscopically consist of a multinodular myxoid mesenchymal proliferation. Bands of sclerotic collagen containing preexisting breast ducts and abundant vascularization are other features typical of NMB. No relation to Carney complex has been reported, and an indolent behavior is the rule in all patients. We present a case of NMB occurring in the nipple of a 46-year-old man and analyze the clinicopathological features of the other cases of NMB reported in the English literature, concluding that two of them most likely correspond to trauma- induced cutaneous focal mucinosis of the mammary areola. Finally, we review diagnostic criteria for NMB and elaborate an ontogenetic hypothesis based on both its morphological resemblance to myofibroblastoma and its immunohistochemical profile. (en)
Title
  • Nodular mucinosis of the breast in a male: reassessment of diagnostic criteria and proposal for its classification as a soft tissue tumor in the myofibroblastoma and spindle cell lipoma spectrum
  • Nodular mucinosis of the breast in a male: reassessment of diagnostic criteria and proposal for its classification as a soft tissue tumor in the myofibroblastoma and spindle cell lipoma spectrum (en)
skos:prefLabel
  • Nodular mucinosis of the breast in a male: reassessment of diagnostic criteria and proposal for its classification as a soft tissue tumor in the myofibroblastoma and spindle cell lipoma spectrum
  • Nodular mucinosis of the breast in a male: reassessment of diagnostic criteria and proposal for its classification as a soft tissue tumor in the myofibroblastoma and spindle cell lipoma spectrum (en)
skos:notation
  • RIV/00216208:11140/14:10227276!RIV15-MSM-11140___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 32687
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11140/14:10227276
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • myofibroblastoma; mucinosis; nipple; breast (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CH - Švýcarská konfederace
http://linked.open...ontrolniKodProRIV
  • [69E4DDC8377E]
http://linked.open...i/riv/nazevZdroje
  • Dermatopathology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 1
http://linked.open...iv/tvurceVysledku
  • Kazakov, Dmitry
  • Ariza, Aurelio
  • Fernández-Figueras, Maria Teresa
  • Martos, Raquel López
  • Ojanguren, Isabel
  • Vila, Jordi
issn
  • 2296-3529
number of pages
http://bibframe.org/vocab/doi
  • 10.1159/000364859
http://localhost/t...ganizacniJednotka
  • 11140
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