About: Stereological methods for quantitative assessment of hepatic microcirculation

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.formatex.info/microscopy5/book/737-748.pdf
Description	This chapter reviews the current knowledge on healthy and pathological hepatic circulation and microcirculation in animal models used in biomedical research and in human histopathology. To demonstrate the clinical importance of this topic, we focus on blood vessels (particularly microvessels) in liver surgery and in hepatic metastasesof colorectal carcinoma. Histological techniques of assessment of healthy and tumourous microvessels are reviewed with focus on the immunohistochemistry on the endothelium, basal lamina and lectin immunohistochemistry. The role of angiogenesis and vascularisation in colorectal cancer and liver metastasis is linked to recent knowledge on proliferation, tumour invasion, metastasis formation, prognostic factors,and scoring systems. In addition tohistopathological methods, the three-dimensional imaging of hepatic microvessels using corrosion casts is shown using X-ray microtomography. Stereological methods are demonstrated to quantify the volume, surface, length, numerical density and tortuosity of the microvessels. This chapter reviews the current knowledge on healthy and pathological hepatic circulation and microcirculation in animal models used in biomedical research and in human histopathology. To demonstrate the clinical importance of this topic, we focus on blood vessels (particularly microvessels) in liver surgery and in hepatic metastasesof colorectal carcinoma. Histological techniques of assessment of healthy and tumourous microvessels are reviewed with focus on the immunohistochemistry on the endothelium, basal lamina and lectin immunohistochemistry. The role of angiogenesis and vascularisation in colorectal cancer and liver metastasis is linked to recent knowledge on proliferation, tumour invasion, metastasis formation, prognostic factors,and scoring systems. In addition tohistopathological methods, the three-dimensional imaging of hepatic microvessels using corrosion casts is shown using X-ray microtomography. Stereological methods are demonstrated to quantify the volume, surface, length, numerical density and tortuosity of the microvessels. (en)
Title	Stereological methods for quantitative assessment of hepatic microcirculation Stereological methods for quantitative assessment of hepatic microcirculation (en)
skos:prefLabel	Stereological methods for quantitative assessment of hepatic microcirculation Stereological methods for quantitative assessment of hepatic microcirculation (en)
skos:notation	RIV/00216208:11140/12:10126231!RIV13-MSM-11140___
http://linked.open...avai/predkladatel	Lékařská fakulta v Plzni
http://linked.open...avai/riv/aktivita	I P S
http://linked.open...avai/riv/aktivity	I, P(ED1.1.00/02.0090), P(ED2.1.00/03.0088), P(NT13326), S
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Liška, Václav Daum, Ondřej Králíčková, Milena Polívka, Jiří Eberlová, Lada Nedorost, Lukáš Skála, Martin Pálek, Richard Králíčková, Anna Kalusová, Kristýna Glanc, David
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Lékařská fakulta v Plzni
http://linked.open...dnocenehoVysledku	171392
http://linked.open...ai/riv/idVysledku	RIV/00216208:11140/12:10126231
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	colorectal carcinoma; micro-computed tomography; immunohistochemistry; quantitative histology; liver (en)
http://linked.open.../riv/klicoveSlovo	immunohistochemistry quantitative histology liver colorectal carcinoma micro-computed tomography
http://linked.open...ontrolniKodProRIV	[EF8337947661]
http://linked.open...i/riv/mistoVydani	Badajoz
http://linked.open...vEdiceCisloSvazku	Vol.1
http://linked.open...i/riv/nazevZdroje	Current microscopy contributions to advances in science and technology
http://linked.open...in/vavai/riv/obor	EA
http://linked.open...ichTvurcuVysledku	11 (xsd:int)
http://linked.open...v/pocetStranKnihy	788 (xsd:int)
http://linked.open...cetTvurcuVysledku	16 (xsd:int)
http://linked.open...vavai/riv/projekt	Centre of the New Technologies and Materials NTIS - New Technologies for Information Society Improvement of resecability of the malignant processes using the more accurate methods for measuring parametres of the remnant liver parenchyma – computer asisted diagnostic and software modeling
http://linked.open...UplatneniVysledku	2012
http://linked.open...iv/tvurceVysledku	Gregor, Tomáš Kochová, Petra Liška, Václav Polívka, Jiří Rohan, Eduard Tonar, Zbyněk Králíčková, Milena Daum, Ondřej Witter, Kirsti Nedorost, Lukáš Eberlová, Lada Králíčková, Anna Glanc, David Kalusová, Kristýna Pálek, Richard Skála, Martin
number of pages	12 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Formatex Research Center
https://schema.org/isbn	978-84-939843-5-9
http://localhost/t...ganizacniJednotka	11140
is http://linked.open...avai/riv/vysledek of	Stereological methods for quantitative assessment of hepatic microcirculation

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