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  • The SITS (Safe Implementation of Thrombolysis in Stroke)-EAST project was launched in 2007 to support evidence-based stroke treatments, including thrombolytic treatments (TLTs), in Central and Eastern Europe. The aim of this study was to detail the topography, efficacy, and specific characteristics of stroke centers in the Czech Republic (CZ), the country with the highest rate of TLT. The nationwide study was performed between September and November 2007 through a questionnaire sent to all centers registered in SITS. The questionnaire contained 25 questions addressing how centers met recommendations for primary and comprehensive stroke centers in 2006. Center characteristics predicting the number of TLTs were identified by multiple regression analysis. Altogether, data were obtained from 42 centers (88% response rate) with the following characteristics [median (min-max)]: catchment area population 150,000 (90,000-750,000); number of strokes/year 420 (150-1,589); number of TLTs 7.5 (2-45); number of physicians specialized in stroke 3 (1-7). Centers treated 4.3% of the patients with ischemic strokes with tissue plasminogen activator. A stroke unit was present in 32 (78%) departments. Rescue interventional therapies were performed in 11 (26%). Financial problems restricted TLT in 14 (35%) centers. Fourteen factors were associated with the number of TLTs in univariate regression analysis, but in multiple regression analysis, only the catchment area population (p\0.001),[3 physicians specialized in stroke (p\0.001), and the presence of an acute interventional program (p\0.006) remained significant. This study provides the fundamental stroke treatment network data that are essential for certification and further SITS-EAST TLT expansion.
  • The SITS (Safe Implementation of Thrombolysis in Stroke)-EAST project was launched in 2007 to support evidence-based stroke treatments, including thrombolytic treatments (TLTs), in Central and Eastern Europe. The aim of this study was to detail the topography, efficacy, and specific characteristics of stroke centers in the Czech Republic (CZ), the country with the highest rate of TLT. The nationwide study was performed between September and November 2007 through a questionnaire sent to all centers registered in SITS. The questionnaire contained 25 questions addressing how centers met recommendations for primary and comprehensive stroke centers in 2006. Center characteristics predicting the number of TLTs were identified by multiple regression analysis. Altogether, data were obtained from 42 centers (88% response rate) with the following characteristics [median (min-max)]: catchment area population 150,000 (90,000-750,000); number of strokes/year 420 (150-1,589); number of TLTs 7.5 (2-45); number of physicians specialized in stroke 3 (1-7). Centers treated 4.3% of the patients with ischemic strokes with tissue plasminogen activator. A stroke unit was present in 32 (78%) departments. Rescue interventional therapies were performed in 11 (26%). Financial problems restricted TLT in 14 (35%) centers. Fourteen factors were associated with the number of TLTs in univariate regression analysis, but in multiple regression analysis, only the catchment area population (p\0.001),[3 physicians specialized in stroke (p\0.001), and the presence of an acute interventional program (p\0.006) remained significant. This study provides the fundamental stroke treatment network data that are essential for certification and further SITS-EAST TLT expansion. (en)
Title
  • A nationwide study on topography and efficacy of the stroke treatment network in the Czech republic
  • A nationwide study on topography and efficacy of the stroke treatment network in the Czech republic (en)
skos:prefLabel
  • A nationwide study on topography and efficacy of the stroke treatment network in the Czech republic
  • A nationwide study on topography and efficacy of the stroke treatment network in the Czech republic (en)
skos:notation
  • RIV/00216208:11140/10:10128563!RIV13-MSM-11140___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NS10100), Z(MSM0021620819)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 244719
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11140/10:10128563
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • republic; Czech; network; treatment; stroke; efficacy; topography; study; nationwide (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [C616F1F91F59]
http://linked.open...i/riv/nazevZdroje
  • Journal of Neurology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 257
http://linked.open...iv/tvurceVysledku
  • Mikulík, Robert
  • Šaňák, Daniel
  • Bar, Michal
  • Ševčík, Petr
  • Wahlgren, Nils
  • Kalita, Zbyněk
  • Václavík, Daniel
http://linked.open...ain/vavai/riv/wos
  • 000273033900005
http://linked.open...n/vavai/riv/zamer
issn
  • 0340-5354
number of pages
http://bibframe.org/vocab/doi
  • 10.1007/s00415-009-5259-3
http://localhost/t...ganizacniJednotka
  • 11140
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