About: Impact of Tumour Cell Death on the Activation of Anti-tumour Immune Response

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The primary function of the immune system is to protect the host against pathogens.Success of vaccination diseases has led to efforts to develop strategies to activate a specific immune response against cancer. However,this task has proved to be very challenging.In the last few years there has been rapid progress in the identification of the molecular mechanisms by which the immune system detects pathogens and initiates immune responses. By contrast, recognition of neoplastic cells lags behind, and induction of specific anti-tumour immunity is even less understood.In this chapter we discuss evidence for the role of the immune system in the control of tumour growth. We also rewiev recent advances in the understanding of mechanisms that can alert the immune system ti the presence of neoplastic lesions, and we discuss recent data on the immunogenicity of tumour cells and their interaction with presenting cells. The primary function of the immune system is to protect the host against pathogens.Success of vaccination diseases has led to efforts to develop strategies to activate a specific immune response against cancer. However,this task has proved to be very challenging.In the last few years there has been rapid progress in the identification of the molecular mechanisms by which the immune system detects pathogens and initiates immune responses. By contrast, recognition of neoplastic cells lags behind, and induction of specific anti-tumour immunity is even less understood.In this chapter we discuss evidence for the role of the immune system in the control of tumour growth. We also rewiev recent advances in the understanding of mechanisms that can alert the immune system ti the presence of neoplastic lesions, and we discuss recent data on the immunogenicity of tumour cells and their interaction with presenting cells. (en)
Title	Impact of Tumour Cell Death on the Activation of Anti-tumour Immune Response Impact of Tumour Cell Death on the Activation of Anti-tumour Immune Response (en)
skos:prefLabel	Impact of Tumour Cell Death on the Activation of Anti-tumour Immune Response Impact of Tumour Cell Death on the Activation of Anti-tumour Immune Response (en)
skos:notation	RIV/00216208:11130/09:5529!RIV10-GA0-11130___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA310/08/0838), Z(MSM0021620812)
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Špíšek, Radek Bartůňková, Jiřina
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 2. lékařská fakulta
http://linked.open...dnocenehoVysledku	318639
http://linked.open...ai/riv/idVysledku	RIV/00216208:11130/09:5529
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Cancer immune-editing; Dendritic cells; Heat shock proteins; Immunogenicity of tumour cells; Immunotherapy; Tumour immunology (en)
http://linked.open.../riv/klicoveSlovo	Immunotherapy Dendritic cells Heat shock proteins Cancer immune-editing Immunogenicity of tumour cells Tumour immunology
http://linked.open...ontrolniKodProRIV	[348376607EE8]
http://linked.open...i/riv/mistoVydani	Belgie
http://linked.open...i/riv/nazevZdroje	Phagocytosis of Dying Cells: From Molecular Mechanism to Human Disease
http://linked.open...in/vavai/riv/obor	EC
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...v/pocetStranKnihy	447 (xsd:int)
http://linked.open...cetTvurcuVysledku	2 (xsd:int)
http://linked.open...vavai/riv/projekt	Generation of dendritic cell-based vaccines for ovarian cancer immunotherapy
http://linked.open...UplatneniVysledku	2009
http://linked.open...iv/tvurceVysledku	Špíšek, Radek Bartůňková, Jiřina
http://linked.open...n/vavai/riv/zamer	Chronická onemocnění vznikající na podkladě nepřiměřené reaktivity imunitního systému, jejich patogeneze a možnosti včasné diagnostiky a léčby
number of pages	24 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Springer-Verlag
https://schema.org/isbn	978-1-4020-9292-3
http://localhost/t...ganizacniJednotka	11130
is http://linked.open...avai/riv/vysledek of	Impact of Tumour Cell Death on the Activation of Anti-tumour Immune Response Impact of Tumour Cell Death on the Activation of Anti-tumour Immune Response Impact of Tumour Cell Death on the Activation of Anti-tumour Immune Response Impact of Tumour Cell Death on the Activation of Anti-tumour Immune Response

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