About: Effect of different magnetic nanoparticle coatings on the efficiency of stem cell labeling

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Maghemite nanoparticles with various coatings were prepared by the coprecipitation method and characterized by transmission electron microscopy, dynamic light scattering and IR in terms of morphology, size, polydispersity and surface coating. The labeling efficiency and the viability of both rat and human mesenchymal stem cells labeled with Endorem (R), poly(L-lysine) (PLL)-modified Endorem (R), uncoated gamma-Fe2O3, D-mannose-, PLL- or poly(N,N-dimethylacrylamide) (PDMAAm)-coated gamma-Fe2O3 nanoparticles were compared. Coated gamma-Fe2O3 nanoparticles labeled cells better than did Endorem (R). High relaxation rates and in vitro magnetic resonance imaging of cells labeled with coated nanoparticles showed clearly visible contrast compared with unlabeled cells or cells labeled with Endorem (R). Maghemite nanoparticles with various coatings were prepared by the coprecipitation method and characterized by transmission electron microscopy, dynamic light scattering and IR in terms of morphology, size, polydispersity and surface coating. The labeling efficiency and the viability of both rat and human mesenchymal stem cells labeled with Endorem (R), poly(L-lysine) (PLL)-modified Endorem (R), uncoated gamma-Fe2O3, D-mannose-, PLL- or poly(N,N-dimethylacrylamide) (PDMAAm)-coated gamma-Fe2O3 nanoparticles were compared. Coated gamma-Fe2O3 nanoparticles labeled cells better than did Endorem (R). High relaxation rates and in vitro magnetic resonance imaging of cells labeled with coated nanoparticles showed clearly visible contrast compared with unlabeled cells or cells labeled with Endorem (R). (en)
Title	Effect of different magnetic nanoparticle coatings on the efficiency of stem cell labeling Effect of different magnetic nanoparticle coatings on the efficiency of stem cell labeling (en)
skos:prefLabel	Effect of different magnetic nanoparticle coatings on the efficiency of stem cell labeling Effect of different magnetic nanoparticle coatings on the efficiency of stem cell labeling (en)
skos:notation	RIV/00216208:11130/09:5416!RIV10-GA0-11130___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0538), P(GA203/09/1242), P(GD309/08/H079), P(KAN200200651), P(KAN201110651), Z(AV0Z40500505), Z(AV0Z50390512)
http://linked.open...iv/cisloPeriodika	10
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Syková, Eva Hájek, Milan Jendelová, Pavla Herynek, Vít
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 2. lékařská fakulta
http://linked.open...dnocenehoVysledku	312067
http://linked.open...ai/riv/idVysledku	RIV/00216208:11130/09:5416
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Magnetic nanoparticles; Maghemite; MRI; Stem cells; Biocompatibility; Contrast agent; iron-oxide nanoparticles; in-vivo tracking; spinal-cord-injury; superparamagnetic nanoparticles; transfection agents; arterial-disease; progenitor cells; contrast agents; transplantation; polymerization (en)
http://linked.open.../riv/klicoveSlovo	Maghemite superparamagnetic nanoparticles MRI transplantation Contrast agent Stem cells contrast agents Magnetic nanoparticles Biocompatibility iron-oxide nanoparticles progenitor cells polymerization arterial-disease in-vivo tracking spinal-cord-injury transfection agents
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[EF6329448EF1]
http://linked.open...i/riv/nazevZdroje	Journal of Magnetism and Magnetic Materials
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Surface-modified magnetic nanoparticles for cell labeling and in vivo and in vitro diagnostics PhD program in neuroscience Center for Cell Therapy and Tissue Repair Nanoparticulate and supramolecular systems for targeted drug delivery Combined contrast agents for molecular MR imaging
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	321
http://linked.open...iv/tvurceVysledku	Syková, Eva Hájek, Milan Jendelová, Pavla Herynek, Vít Trchová, M. Horák, D. Babič, M. Kapcalova, M. Likavcanova, K.
http://linked.open...ain/vavai/riv/wos	000265278000048
http://linked.open...n/vavai/riv/zamer	Progresivní makromolekulární materiály a supramolekulární systémy: syntéza a studium vlastností, jevů a možností využití pro speciální aplikace a moderní technologie Molekulární, buněčné a systémové mechanizmy závažných onemocnění lidského organizmu, jejich diagnostika, terapie a farmakoterapie
issn	0304-8853
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	11130
is http://linked.open...avai/riv/vysledek of	Effect of different magnetic nanoparticle coatings on the efficiency of stem cell labeling Effect of different magnetic nanoparticle coatings on the efficiency of stem cell labeling Effect of different magnetic nanoparticle coatings on the efficiency of stem cell labeling Effect of different magnetic nanoparticle coatings on the efficiency of stem cell labeling

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