About: Genetic Modifiers of Liver Disease in Cystic Fibrosis

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Genetic Modifiers of Liver Disease in Cystic Fibrosis Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Context A subset (approximate to 3%-5%) of patients with cystic fibrosis (CF) develops severe liver disease with portal hypertension. Objective To assess whether any of 9 polymorphisms in 5 candidate genes (alpha(1)-antitrypsin or alpha(1)-antiprotease [SERPINA1], angiotensin-converting enzyme [ACE], glutathione S-transferase [GSTP1], mannose-binding lectin 2 [MBL2], and transforming growth factor beta 1 [TGFB1]) are associated with severe liver disease in patients with CF. Context A subset (approximate to 3%-5%) of patients with cystic fibrosis (CF) develops severe liver disease with portal hypertension. Objective To assess whether any of 9 polymorphisms in 5 candidate genes (alpha(1)-antitrypsin or alpha(1)-antiprotease [SERPINA1], angiotensin-converting enzyme [ACE], glutathione S-transferase [GSTP1], mannose-binding lectin 2 [MBL2], and transforming growth factor beta 1 [TGFB1]) are associated with severe liver disease in patients with CF. (en)
Title	Genetic Modifiers of Liver Disease in Cystic Fibrosis Genetic Modifiers of Liver Disease in Cystic Fibrosis (en)
skos:prefLabel	Genetic Modifiers of Liver Disease in Cystic Fibrosis Genetic Modifiers of Liver Disease in Cystic Fibrosis (en)
skos:notation	RIV/00216208:11130/09:5337!RIV10-MZ0-11130___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NR9448), Z(MZ0FNM2005)
http://linked.open...iv/cisloPeriodika	10
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Macek jr., Milan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 2. lékařská fakulta
http://linked.open...dnocenehoVysledku	316157
http://linked.open...ai/riv/idVysledku	RIV/00216208:11130/09:5337
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	transmembrane conductance regulator; alpha-1-antitrypsin deficiency; lung-disease; risk-factors; alpha(1)-antitrypsin deficiency; severity; epidemiology; association; expression; cirrhosis (en)
http://linked.open.../riv/klicoveSlovo	alpha(1)-antitrypsin deficiency alpha-1-antitrypsin deficiency transmembrane conductance regulator association epidemiology expression lung-disease risk-factors severity cirrhosis
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[C363FAFB46C2]
http://linked.open...i/riv/nazevZdroje	JAMA-Journal of The American Medical Association
http://linked.open...in/vavai/riv/obor	FP
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	313 (xsd:int)
http://linked.open...vavai/riv/projekt	Polymorphisms in FSH- and androgen receptor genes and in the CFTR gene in the pathogenesis of severe reproductive disorders and in pharmacogenetic prevention of ovarian hyperstimulation syndrome
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	302
http://linked.open...iv/tvurceVysledku	Bell, SC Macek jr., Milan Zemková, Daniela Castellani, C. Wilschanski, M. Zielenski, J. Bartlett, JR Dorfman, R. Bourke, B. Castaldo, G. Cipolli, M. Colombo, C. Colombo, J. L. Corey, M. Debray, D. Drumm, M. L. Durie, PR Fernandez, A. Friedman, KJ Hannah, WB Knowles, M. R. Lacaille, F. Lange, EM Ling, SC Pace, R. G. Phillips, M. J. Rowland, M. Salvatore, F. Silverman, LM Taylor, CJ Wainwright, C. Wang, YF Wright, FA Zou, F.
http://linked.open...ain/vavai/riv/wos	000269616200025
http://linked.open...n/vavai/riv/zamer	Zdokonalení časné diagnostiky, prevence a léčby těžkých vrozených vývojových vad a chorob geneticky podmíněných či s genetickou dispozicí v prenatální a postnatální fázi vývoje
issn	0098-7484
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	11130
is http://linked.open...avai/riv/vysledek of	Genetic Modifiers of Liver Disease in Cystic Fibrosis Genetic Modifiers of Liver Disease in Cystic Fibrosis Genetic Modifiers of Liver Disease in Cystic Fibrosis Genetic Modifiers of Liver Disease in Cystic Fibrosis

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 36 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software