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Description
| - Background/Aims: To assess, in a prospective cohort study of 238 renal transplant patients, our hypothesis that elevated ADMA levels may be influenced by physical exercise and obesity. Methods: Blood samples before and after six months were obtained from 116 transplant patients participating in an aerobic exercise (Group I). A control group consisted of 122 matched transplant patients who did not exercise regularly (Group II). Results: There were no significant differences in ADMA levels between both groups before the training program (Group I-B vs Group IIB). After six months of exercise, ADMA levels in Group I decreased (Group I-B vs Group I-A: 3.50 +/- 0.45 vs 2.11 +/- 0.35 mu mol/L; p < 0.01) and were lower compared to those in Group II (Group I-A vs Group IIA : 2.11 +/- 0.23 vs 3.25 +/- 0.34 mu mol/L; p < 0.01). Analysis of our results in obese renal transplant recipients (BMI >= 30 kg/m(2)) confirmed a smaller effect of exercise training (Group I-BO vs Group I-AO: 3.75 +/- 0.52 vs 3.45 +/- 0.45; p < 0.05 and Group I-AO vs Group IIAO: 3.45 +/- 0.45 vs 3.74 +/- 0.62; p < 0.05). Blood lipids, HbA(1c), insulin, and systolic BP were also affected by the training program. Conclusion: Elevated ADMA levels were significantly decreased by early exercise after renal transplantation. The effect of exercise was smaller in obese patients.
- Background/Aims: To assess, in a prospective cohort study of 238 renal transplant patients, our hypothesis that elevated ADMA levels may be influenced by physical exercise and obesity. Methods: Blood samples before and after six months were obtained from 116 transplant patients participating in an aerobic exercise (Group I). A control group consisted of 122 matched transplant patients who did not exercise regularly (Group II). Results: There were no significant differences in ADMA levels between both groups before the training program (Group I-B vs Group IIB). After six months of exercise, ADMA levels in Group I decreased (Group I-B vs Group I-A: 3.50 +/- 0.45 vs 2.11 +/- 0.35 mu mol/L; p < 0.01) and were lower compared to those in Group II (Group I-A vs Group IIA : 2.11 +/- 0.23 vs 3.25 +/- 0.34 mu mol/L; p < 0.01). Analysis of our results in obese renal transplant recipients (BMI >= 30 kg/m(2)) confirmed a smaller effect of exercise training (Group I-BO vs Group I-AO: 3.75 +/- 0.52 vs 3.45 +/- 0.45; p < 0.05 and Group I-AO vs Group IIAO: 3.45 +/- 0.45 vs 3.74 +/- 0.62; p < 0.05). Blood lipids, HbA(1c), insulin, and systolic BP were also affected by the training program. Conclusion: Elevated ADMA levels were significantly decreased by early exercise after renal transplantation. The effect of exercise was smaller in obese patients. (en)
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Title
| - Early Exercise Training After Renal Transplantation and Asymmetric Dimethylarginine: The Effect of Obesity
- Early Exercise Training After Renal Transplantation and Asymmetric Dimethylarginine: The Effect of Obesity (en)
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skos:prefLabel
| - Early Exercise Training After Renal Transplantation and Asymmetric Dimethylarginine: The Effect of Obesity
- Early Exercise Training After Renal Transplantation and Asymmetric Dimethylarginine: The Effect of Obesity (en)
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skos:notation
| - RIV/00216208:11120/14:43909227!RIV15-MSM-11120___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11120/14:43909227
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Obesity; ADMA; Physical Exercise; Renal Transplantation (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - CH - Švýcarská konfederace
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Kidney & Blood Pressure Research
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Gürlich, Robert
- Teplan-jr, Vladimír
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://bibframe.org/vocab/doi
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http://localhost/t...ganizacniJednotka
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