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Description
  • Pituitary hormone and cytokine prolactin (PRL) is one of the mediators of the bidirectional communication between neuroendocrine and immune systems. It participates in many immunomodulatory activities, affects differentiation and maturation of both, B and T lymphocytes and enhances inflammatory responses and production of immunoglobulins. Hyperprolactinemia has been described in many autoimmune diseases, both systemic (SLE, RA, PsA) and organ-specific (T1D, CD and others) and the activity of PRL has been intensively studied. Nevertheless, no data on PRL contribution to pathogenesis of diabetes mellitus is available, although the effect of PRL on β cells of the pancreas and insulin secretion has been observed.
  • Pituitary hormone and cytokine prolactin (PRL) is one of the mediators of the bidirectional communication between neuroendocrine and immune systems. It participates in many immunomodulatory activities, affects differentiation and maturation of both, B and T lymphocytes and enhances inflammatory responses and production of immunoglobulins. Hyperprolactinemia has been described in many autoimmune diseases, both systemic (SLE, RA, PsA) and organ-specific (T1D, CD and others) and the activity of PRL has been intensively studied. Nevertheless, no data on PRL contribution to pathogenesis of diabetes mellitus is available, although the effect of PRL on β cells of the pancreas and insulin secretion has been observed. (en)
Title
  • Immunomodulatory role of prolactin in diabetes development
  • Immunomodulatory role of prolactin in diabetes development (en)
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  • Immunomodulatory role of prolactin in diabetes development
  • Immunomodulatory role of prolactin in diabetes development (en)
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  • RIV/00216208:11120/09:00001723!RIV10-MSM-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM0021620814)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 318558
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/09:00001723
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Immunity; Monocytes; Prolactin; T1D; T2D (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [98B4ECDEC26D]
http://linked.open...i/riv/nazevZdroje
  • Autoimmunity Reviews
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 9
http://linked.open...iv/tvurceVysledku
  • Černá, Marie
  • Čejková, Pavlína
  • Fojtíková, Markéta
http://linked.open...ain/vavai/riv/wos
  • 000270473100005
http://linked.open...n/vavai/riv/zamer
issn
  • 1568-9972
number of pages
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  • 11120
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