About: Effect of methamphetamine exposure and cross-fostering on sensorimotor development of male and female rat pups     Goto   Sponge   NotDistinct   Permalink

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  • Prenatální expozice metamfetaminu negativně ovlivňuje mateřské chování a postnatální vývoj mláďat. Naše nejnovější poznatky ukazují, že zpoždění ve vývoji senzorimotorických funkcí je možné ovlivnit výchovou adoptivní kontrolní matkou. (cs)
  • The present study tested the hypothesis that cross-fostering influences the development of rat pups. Mothers were exposed daily to injection of methamphetamine (M) (5 mg/kg) or saline for 9 weeks: 3 weeks prior to impregnation, throughout gestation and lactation periods. Control females animals without any injections were used. On postnatal day (PD) 1, pups were cross-fostered so that each mother received four pups of her own and eight pups from the mothers with the other two treatments. Offspring were tested for sensorimotor development in preweaning period by using tests of: negative geotaxis, tail pull, righting reflexes, rotarod and bar-holding. Further: the pups were weighed daily. Our results showed that birth weight in prenatally M-exposed pups was lower than in control or saline-exposed pups. Prenatally M-exposed pups gained less weight than control or saline-exposed pups regardless of postnatal treatment and sex. Further our data demonstrated that prenatal and postnatal M exposure impairs eff
  • The present study tested the hypothesis that cross-fostering influences the development of rat pups. Mothers were exposed daily to injection of methamphetamine (M) (5 mg/kg) or saline for 9 weeks: 3 weeks prior to impregnation, throughout gestation and lactation periods. Control females animals without any injections were used. On postnatal day (PD) 1, pups were cross-fostered so that each mother received four pups of her own and eight pups from the mothers with the other two treatments. Offspring were tested for sensorimotor development in preweaning period by using tests of: negative geotaxis, tail pull, righting reflexes, rotarod and bar-holding. Further: the pups were weighed daily. Our results showed that birth weight in prenatally M-exposed pups was lower than in control or saline-exposed pups. Prenatally M-exposed pups gained less weight than control or saline-exposed pups regardless of postnatal treatment and sex. Further our data demonstrated that prenatal and postnatal M exposure impairs eff (en)
Title
  • Effect of methamphetamine exposure and cross-fostering on sensorimotor development of male and female rat pups
  • Effect of methamphetamine exposure and cross-fostering on sensorimotor development of male and female rat pups (en)
  • Vliv expozice metamfetaminu a cross-fosteringu na senzorimotorický vývoj samčích a samičích potkaních mláďat (cs)
skos:prefLabel
  • Effect of methamphetamine exposure and cross-fostering on sensorimotor development of male and female rat pups
  • Effect of methamphetamine exposure and cross-fostering on sensorimotor development of male and female rat pups (en)
  • Vliv expozice metamfetaminu a cross-fosteringu na senzorimotorický vývoj samčích a samičích potkaních mláďat (cs)
skos:notation
  • RIV/00216208:11120/09:00000490!RIV09-MZ0-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(1A8610), P(LC554), Z(MSM0021620816)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 312170
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/09:00000490
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • methamphetamine; sensorimotor development; cross-fostering; drug abuse (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [9342BA697AC5]
http://linked.open...i/riv/nazevZdroje
  • Developmental Psychobiology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 51
http://linked.open...iv/tvurceVysledku
  • Hrubá, Lenka
  • Pometlová, Marie
  • Rokyta, Richard
  • Schutová, Barbora
  • Šlamberová, Romana
http://linked.open...ain/vavai/riv/wos
  • 000262459400007
http://linked.open...n/vavai/riv/zamer
issn
  • 0012-1630
number of pages
http://localhost/t...ganizacniJednotka
  • 11120
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