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| rdf:type
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| Description
| - Studie zkoumající sérové hladiny resistinu u benigní hyperplazie prostaty a karcinomu prostaty. Sérum bylo odebráno od 26 pacientů s benigní hyperplázií a 42 pacientů s karcinome prostaty (z toho bylo 18 se stádiem pT2 a 24 se stádiem pT3. Sérové hladiny resistinu se nelšily statisticky významně mezi BPH a karcinomem, ale byl pozorován trend směrem k poklesu s vyšším stagem onemocnění. Sérové hladiny byly významně nižší u pacientů s invazí nádoru do semenných váčků. U BPH korelovaly sérové hladiny resistinu s inzulínovou rezistencí, zánětlivými parametry a kortizonem, u karcinomu prostaty pak s poměrem F/T PSA a kortizonem. Imunohistochemie neukázala žádné rozdíly v intenzitě barvení tkání. (cs)
- Resistin is a member of adipokine family involved in the regulation of inflammatory reactions and insulin sensitivity. In presented study its possible role in the development of benign prostate hyperplasia and prostate cancer was evaluated. Blood samples and prostate specimens were collected from 26 patients with benign prostate hyperplasia (BPH) and from 42 patients with prostate cancer (PCa) stage pT2 (n=18) and pT3 (n=24). Selected metabolic and biochemical parameters and serum resistin levels were measured and anthropometric measurements were performed as well as tissue immunohistochemistry for resistin. Serum resistin levels did not differ significantly between benign hyperplasia and prostate cancer but in cancer patients there was a trend towards decrease with higher cancer stage. Moreover, serum resistin levels were significantly lower in patients with seminal vesicle invasion in comparison to those without invasion. While in BPH serum resistin levels correlated with insulin resistance, inflamm
- Resistin is a member of adipokine family involved in the regulation of inflammatory reactions and insulin sensitivity. In presented study its possible role in the development of benign prostate hyperplasia and prostate cancer was evaluated. Blood samples and prostate specimens were collected from 26 patients with benign prostate hyperplasia (BPH) and from 42 patients with prostate cancer (PCa) stage pT2 (n=18) and pT3 (n=24). Selected metabolic and biochemical parameters and serum resistin levels were measured and anthropometric measurements were performed as well as tissue immunohistochemistry for resistin. Serum resistin levels did not differ significantly between benign hyperplasia and prostate cancer but in cancer patients there was a trend towards decrease with higher cancer stage. Moreover, serum resistin levels were significantly lower in patients with seminal vesicle invasion in comparison to those without invasion. While in BPH serum resistin levels correlated with insulin resistance, inflamm (en)
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| Title
| - Serum resistin levels in benign prostate hyperplasia and non-metastatic prostate cancer: possible role in cancer progression
- Serum resistin levels in benign prostate hyperplasia and non-metastatic prostate cancer: possible role in cancer progression (en)
- Sérové hladiny rezistinu u benigní hyperplazie a nemetastazujícího karcinomu prostaty: možná úloha v nádorové progresi (cs)
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| skos:prefLabel
| - Serum resistin levels in benign prostate hyperplasia and non-metastatic prostate cancer: possible role in cancer progression
- Serum resistin levels in benign prostate hyperplasia and non-metastatic prostate cancer: possible role in cancer progression (en)
- Sérové hladiny rezistinu u benigní hyperplazie a nemetastazujícího karcinomu prostaty: možná úloha v nádorové progresi (cs)
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| skos:notation
| - RIV/00216208:11120/08:00001265!RIV09-MZ0-11120___
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| http://linked.open...avai/riv/aktivita
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| http://linked.open...avai/riv/aktivity
| - Z(MZ00000064165), Z(MZ0VFN2005)
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| http://linked.open...iv/cisloPeriodika
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| http://linked.open...vai/riv/dodaniDat
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| http://linked.open...aciTvurceVysledku
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| http://linked.open.../riv/druhVysledku
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| http://linked.open...iv/duvernostUdaju
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| http://linked.open...titaPredkladatele
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| http://linked.open...dnocenehoVysledku
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| http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11120/08:00001265
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| http://linked.open...riv/jazykVysledku
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| http://linked.open.../riv/klicovaSlova
| - Immunohistochemistry; inflammation; insulin resistance; prostate cancer; resisstin (en)
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| http://linked.open.../riv/klicoveSlovo
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| http://linked.open...odStatuVydavatele
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| http://linked.open...ontrolniKodProRIV
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| http://linked.open...i/riv/nazevZdroje
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| http://linked.open...in/vavai/riv/obor
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| http://linked.open...ichTvurcuVysledku
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| http://linked.open...cetTvurcuVysledku
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| http://linked.open...UplatneniVysledku
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| http://linked.open...v/svazekPeriodika
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| http://linked.open...iv/tvurceVysledku
| - Kuncová, Jitka
- Čechák, Petr
- Haluzík, M.
- Vernerová, Zdeňka
- Housa, Daniel
- Heráček, Jiří
- Rosová, Blanka
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| http://linked.open...ain/vavai/riv/wos
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| http://linked.open...n/vavai/riv/zamer
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| issn
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| number of pages
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| http://localhost/t...ganizacniJednotka
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| is http://linked.open...avai/riv/vysledek
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