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Description
  • Motor cortex stimulation (MCS) has gained a significant role in treatment of neuropathic pain. In order to evaluate effect of MCS in experimental animals we applied MCS to rats with neuropathic pain, which was evoked by chronic constriction injury (CCI) to the left sciatic nerve. Pain thresholds of both hind limbs were measured before, immediately after MCS, 1 h after MCS and 1 day after MCS. Effect of the stimulation was studied with respect to laterality (contralateral and ipsilateral MCS) and duration (short-term 10-min and long-term 1-h stimulation). It was found out that in control rats MCS did not affect thermal nociceptive thresholds. However, in CCI animals following results were obtained: difference score (difference in paw withdrawal latency between ligated and non-ligated hind limb) significantly decreased after both short- and long-term contralateral MCS; the difference score after the long-term ipsilateral MCS (related to the ligated hind limb) was not significantly different from that of
  • Motor cortex stimulation (MCS) has gained a significant role in treatment of neuropathic pain. In order to evaluate effect of MCS in experimental animals we applied MCS to rats with neuropathic pain, which was evoked by chronic constriction injury (CCI) to the left sciatic nerve. Pain thresholds of both hind limbs were measured before, immediately after MCS, 1 h after MCS and 1 day after MCS. Effect of the stimulation was studied with respect to laterality (contralateral and ipsilateral MCS) and duration (short-term 10-min and long-term 1-h stimulation). It was found out that in control rats MCS did not affect thermal nociceptive thresholds. However, in CCI animals following results were obtained: difference score (difference in paw withdrawal latency between ligated and non-ligated hind limb) significantly decreased after both short- and long-term contralateral MCS; the difference score after the long-term ipsilateral MCS (related to the ligated hind limb) was not significantly different from that of (en)
  • U modelu neuropatické bolesti jsme prokázali antinocicepční účinek elektrické stimulace jak kontralaterální, tak ipsilaterální motorické mozkové kůry. (cs)
Title
  • Motor cortex stimulation in rats with chronic constriction injury
  • Motor cortex stimulation in rats with chronic constriction injury (en)
  • Elektricka stimulace mozkove kůry u potkanů s chronickou konstrikcí sedacího nervu (cs)
skos:prefLabel
  • Motor cortex stimulation in rats with chronic constriction injury
  • Motor cortex stimulation in rats with chronic constriction injury (en)
  • Elektricka stimulace mozkove kůry u potkanů s chronickou konstrikcí sedacího nervu (cs)
skos:notation
  • RIV/00216208:11120/08:00000797!RIV09-MSM-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(LC554), Z(MSM0021620816)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 380704
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/08:00000797
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • motor cortex stimulation; chronic constriction injury; pain thresholds (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [37744C0427BF]
http://linked.open...i/riv/nazevZdroje
  • Experimental Brain Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 185
http://linked.open...iv/tvurceVysledku
  • Rokyta, Richard
  • Yamamotová, Anna
  • Franěk, Miloslav
  • Vaculín, Šimon
http://linked.open...ain/vavai/riv/wos
  • 000252942700016
http://linked.open...n/vavai/riv/zamer
issn
  • 0014-4819
number of pages
http://localhost/t...ganizacniJednotka
  • 11120
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