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Description
  • Adipose tissue is a major source of nonesterified fatty acids, which are involved in the etiopathogenesis of several metabolic diseases. Mechanisms regulating the processes of lipolysis are of major importance because they represent potential drug targets. Physical exercise is a cost-effective prevention strategy and important therapy for civilization diseases and is an important physiological stimulus of lipolysis in adipose tissue. Besides the traditional role of catecholamines in the regulation of lipolysis, other recently described lipolytic factors, for example, atrial natriuretic peptide and IL-6, are discussed in the context of lipolysis. In vitro as well as in vivo studies provide a substantial amount of data, which are sometimes contradictory. Exercise modifies the functional balance between p and a adrenergic receptors, increases atrial natriuretic peptide-induced lipolysis and improves sensitivity of adipose tissue to insulin. Actual lipolytic rate is the summary of these complex interactio
  • Adipose tissue is a major source of nonesterified fatty acids, which are involved in the etiopathogenesis of several metabolic diseases. Mechanisms regulating the processes of lipolysis are of major importance because they represent potential drug targets. Physical exercise is a cost-effective prevention strategy and important therapy for civilization diseases and is an important physiological stimulus of lipolysis in adipose tissue. Besides the traditional role of catecholamines in the regulation of lipolysis, other recently described lipolytic factors, for example, atrial natriuretic peptide and IL-6, are discussed in the context of lipolysis. In vitro as well as in vivo studies provide a substantial amount of data, which are sometimes contradictory. Exercise modifies the functional balance between p and a adrenergic receptors, increases atrial natriuretic peptide-induced lipolysis and improves sensitivity of adipose tissue to insulin. Actual lipolytic rate is the summary of these complex interactio (en)
  • Tuková tkáň je hlavním zdrojem volných mastných kyselin, které jsou součástí etiopatogeneze metabolických chorob. Mechanismy regulující lipolýzu jaou velmi důležité a reprezentují potenciální lekové cíle. Pohybová aktivita je výhodný nástroj k terpaii civilizačních onemocnění a zároveň mocným stimulem lipolytické kaskády v adipocytech. Vedle úlohy katecholaminů v regulaci lipolýzy je rovněž diskutována úloha hormonů a lokálních působků uvolňovaných v tukové tkáni a majících vliv na regulaci lipolýzy. Cvičení dále modifikuje funkční rovnováhu v adrenergni regulaci lipolýzy. Aktuální úroveň lipolýzy je pak souhrou mnoha komplexních interakcí. (cs)
Title
  • Effect of Exercise on Lipolysis in Adipose Tissue
  • Efekt cvičení na lipolýzu v tukové tkáni (cs)
  • Effect of Exercise on Lipolysis in Adipose Tissue (en)
skos:prefLabel
  • Effect of Exercise on Lipolysis in Adipose Tissue
  • Efekt cvičení na lipolýzu v tukové tkáni (cs)
  • Effect of Exercise on Lipolysis in Adipose Tissue (en)
skos:notation
  • RIV/00216208:11120/08:00000788!RIV09-MSM-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM0021620814)
http://linked.open...iv/cisloPeriodika
  • 5
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 365074
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/08:00000788
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Adipose Tissue; Aerobic Training; Catecholamines; Exercise; Lipolysis; Strength Training; Atrial-Natriuretic-Peptide; Human Skeletal-Muscle; Human Fat-Cells; Catecholamine-Induced Lipolysis; Endurance Training Increases; Necrosis-Factor-Alpha; Epinephrine-Induced Lipolysis; Improves Insulin Sensitivity; Type-2 Diabetic-Patients; Growth-Hormone (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [F09320853F51]
http://linked.open...i/riv/nazevZdroje
  • Future Lipidology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 3
http://linked.open...iv/tvurceVysledku
  • Polák, Jan
  • Štich, Vladimír
  • Bajzová, Magda
http://linked.open...ain/vavai/riv/wos
  • 000260284200012
http://linked.open...n/vavai/riv/zamer
issn
  • 1746-0875
number of pages
http://localhost/t...ganizacniJednotka
  • 11120
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