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Description
| - Spinal cord stimulation (SCS) consisting of electrical stimulation of the dorsal spinal cord using epidural electrodes has been shown to relieve chronic neuropathic pain. To analyze the cerebral activation patterns related to SCS, and to evaluate the effects of SCS on the processing of acute experimental pain, we performed functional magnetic resonance imaging (fMRI) on eight patients suffering from failed back surgery syndrome who were also being treated with SCS for severe pain in their legs and lower back. Three types of stimulation were used, each lasting 36s: (i) SCS, (ii) heat pain (HP) applied to the leg affected by neuropathic pain, and (iii) simultaneous HP and SCS. During SCS, we found increased activation of the medial primary sensorimotor cortex somatotopically corresponding to the foot and/or perineal region, contralateral posterior insula, and the ipsilateral secondary somatosensory cortex (S2).
- Spinal cord stimulation (SCS) consisting of electrical stimulation of the dorsal spinal cord using epidural electrodes has been shown to relieve chronic neuropathic pain. To analyze the cerebral activation patterns related to SCS, and to evaluate the effects of SCS on the processing of acute experimental pain, we performed functional magnetic resonance imaging (fMRI) on eight patients suffering from failed back surgery syndrome who were also being treated with SCS for severe pain in their legs and lower back. Three types of stimulation were used, each lasting 36s: (i) SCS, (ii) heat pain (HP) applied to the leg affected by neuropathic pain, and (iii) simultaneous HP and SCS. During SCS, we found increased activation of the medial primary sensorimotor cortex somatotopically corresponding to the foot and/or perineal region, contralateral posterior insula, and the ipsilateral secondary somatosensory cortex (S2). (en)
- Je prokázáno, že elektrická stimulace míchy snižuje chronickou neuropatickou bolest. Sledovali jsme pacienty pomocí funkční magnetické resonance (FMRI), kteří trpěli bolestmi po neúspěšném operačním řešení bolestí dolních zad. Během stimulace míchy jsme nalezli aktivitu mediální části sensorimotorické kůry somatotopicky odpovídající noze a perineální oblasti. Dále byla aktivována oblast zadní insuly a ipsilaterální sekundární somatosensorická kůra (SZ). Snížení aktivace bylo možno pozorovat v obou motorických oblastech a sensorických oblastech pro ramena, loket a ruku. Temporální oblasti a mozeček byly též aktivovány. Aktivace některých oblastí přímo interferuje se zpracováním neuropatické bolesti. (cs)
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Title
| - Functional magnetic resonance imaging of cerebral activation during spinal cord stimulation in failed back surgery syndrome patients
- Functional magnetic resonance imaging of cerebral activation during spinal cord stimulation in failed back surgery syndrome patients (en)
- Zobrazení aktivace mozku pomocí funkční magnetické resonance během stimulace míchy po neúspěšném operačním řešení bolestí dolních zad (cs)
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skos:prefLabel
| - Functional magnetic resonance imaging of cerebral activation during spinal cord stimulation in failed back surgery syndrome patients
- Functional magnetic resonance imaging of cerebral activation during spinal cord stimulation in failed back surgery syndrome patients (en)
- Zobrazení aktivace mozku pomocí funkční magnetické resonance během stimulace míchy po neúspěšném operačním řešení bolestí dolních zad (cs)
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skos:notation
| - RIV/00216208:11120/08:00000553!RIV09-GA0-11120___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(1M0517), P(GA309/04/0160), P(LC554), P(NR8232), Z(MSM0021620816)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11120/08:00000553
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - spinal cord stimulation; FMRI; neuropathic pain; motor cortex; failed back surgery syndrome (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Stančák, Andrej
- Vrba, I.
- Vrána, Jiří
- Tintěra, Jaroslav
- Kozák, J.
- Poláček, Hubert
- Stančák, M.
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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