About: Visfatin expression in subcutaneous adipose tissue of pre-menopausal women: relation to hormones and weight reduction     Goto   Sponge   NotDistinct   Permalink

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  • Background: A novel adipokine, visfatin, was found to be related to adiposity in humans and regulated by a number of hormonal signals. The aim of this study was to investigate the relationships of visfatin expression in adipose tissue with potential regulatory factors such as insulin, testosterone and tumor necrosis factor-alpha (TNF-alpha) and to elucidate the effect of a diet induced weight reduction on adipose tissue mRNA expression and plasma levels of visfatin. MATERIALS AND METHODS: Biopsies of subcutaneous abdominal adipose tissue (SCAAT) and plasma samples were obtained at the beginning of the study from 47 pre-menopausal women (age 38.7 +/- 1.7 years, body mass index (BMI) 27.9 +/- 1.4 kg m(-2)), consisting of 15 lean, 16 overweight and 16 obese subjects. The subgroup of 32 overweight/obese women (age 42.1 +/- 1.9 years, BMI 31.2 +/- 0.9 kg m(-2)) underwent a 12 week hypocaloric weight reducing diet and samples were obtained at the end of the diet. Biopsy samples were analysed for visfatin an
  • Background: A novel adipokine, visfatin, was found to be related to adiposity in humans and regulated by a number of hormonal signals. The aim of this study was to investigate the relationships of visfatin expression in adipose tissue with potential regulatory factors such as insulin, testosterone and tumor necrosis factor-alpha (TNF-alpha) and to elucidate the effect of a diet induced weight reduction on adipose tissue mRNA expression and plasma levels of visfatin. MATERIALS AND METHODS: Biopsies of subcutaneous abdominal adipose tissue (SCAAT) and plasma samples were obtained at the beginning of the study from 47 pre-menopausal women (age 38.7 +/- 1.7 years, body mass index (BMI) 27.9 +/- 1.4 kg m(-2)), consisting of 15 lean, 16 overweight and 16 obese subjects. The subgroup of 32 overweight/obese women (age 42.1 +/- 1.9 years, BMI 31.2 +/- 0.9 kg m(-2)) underwent a 12 week hypocaloric weight reducing diet and samples were obtained at the end of the diet. Biopsy samples were analysed for visfatin an (en)
  • Novoobjaveny adipokin, visfatin, se dava do souvisu s obezitou u lidi a je regulovaný vicerými hormonálnimi signálmi. Cílem teto studie bylo sledovat vztah exprese visfatinu v tukové tkání s potenciálnimi regulačnými faktormi jako je inzulin, testosterone a TNFa a sledovat efekt diety na hladiny mRNA v tukové tkáni a plazmatické hladiny visfatinu. (cs)
Title
  • Visfatin expression in subcutaneous adipose tissue of pre-menopausal women: relation to hormones and weight reduction
  • Exprese visfatinu v podkožní tukové tkáni u premenopausálích žen: vztah k hladinám hormonů a redukce váhy (cs)
  • Visfatin expression in subcutaneous adipose tissue of pre-menopausal women: relation to hormones and weight reduction (en)
skos:prefLabel
  • Visfatin expression in subcutaneous adipose tissue of pre-menopausal women: relation to hormones and weight reduction
  • Exprese visfatinu v podkožní tukové tkáni u premenopausálích žen: vztah k hladinám hormonů a redukce váhy (cs)
  • Visfatin expression in subcutaneous adipose tissue of pre-menopausal women: relation to hormones and weight reduction (en)
skos:notation
  • RIV/00216208:11120/08:00000539!RIV09-MZ0-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NR9161), Z(MSM0021620814)
http://linked.open...iv/cisloPeriodika
  • 7
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 402791
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/08:00000539
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Adipose tissue; mRNA expression; obesity; TNF-α; visfatin; weight reduction (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [59624BEED984]
http://linked.open...i/riv/nazevZdroje
  • European Journal of Clinical Investigation
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 38
http://linked.open...iv/tvurceVysledku
  • Kováčová, Zuzana
  • Polák, Jan
  • Štich, Vladimír
  • Bajzová, Magda
  • Hejnová, Jindřiška
  • Klimčáková, Eva
  • Kováčiková, Michaela
  • Vítková, Michaela
  • Langin, D.
  • Viguerie, N.
http://linked.open...ain/vavai/riv/wos
  • 000256686000009
http://linked.open...n/vavai/riv/zamer
issn
  • 0014-2972
number of pages
http://localhost/t...ganizacniJednotka
  • 11120
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