About: Intracoronary injection of autologous bone marrow-derived mononuclear cells in patients with large anterior acute myocardial infarction: a prematurely terminated randomized study     Goto   Sponge   NotDistinct   Permalink

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Description
  • V této randomizované studii jsme testovali bezpečnost a efekty intrakoronární injekce kmenových buněk kostní dřeně u 27 pacientů s velkým akutním infarktem myokardu přední stěny ošetřeným primární PCI. Ukázali jsme, že injekce kmenových buněk kostní dřeně do infarktové tepny nezlepší návrat kontraktilní funkce a remodelaci levé komory po 4 měsících ve srovnání s kontrolními pacienty (cs)
  • We designed a randomized study to test the safety and efficacy of intracoronary injection of autologous bone marrow-derived mononuclear cells (BMNCs) in patients with large acute anterior myocardial infarction and late presentation, who were treated with successful primary PCI. Eligible patients were randomly assigned in 2:1 ratio either to intracoronary BMNCs injection (n=17) or standard medical therapy (n=10). This randomized study showed that intracoronary infusion of BMNCs in the infarct-related coronary artery does neither increase recovery of LV ejection fraction, nor reduce LV volumes and infarct size at 4 months, as compared to controls
  • We designed a randomized study to test the safety and efficacy of intracoronary injection of autologous bone marrow-derived mononuclear cells (BMNCs) in patients with large acute anterior myocardial infarction and late presentation, who were treated with successful primary PCI. Eligible patients were randomly assigned in 2:1 ratio either to intracoronary BMNCs injection (n=17) or standard medical therapy (n=10). This randomized study showed that intracoronary infusion of BMNCs in the infarct-related coronary artery does neither increase recovery of LV ejection fraction, nor reduce LV volumes and infarct size at 4 months, as compared to controls (en)
Title
  • Intracoronary injection of autologous bone marrow-derived mononuclear cells in patients with large anterior acute myocardial infarction: a prematurely terminated randomized study
  • Intrakoronární injekce kmenových buněk kostní dřeně u pacientů s velkým předním infarktem myokardu: předčasně ukončená randomizovaná studie (cs)
  • Intracoronary injection of autologous bone marrow-derived mononuclear cells in patients with large anterior acute myocardial infarction: a prematurely terminated randomized study (en)
skos:prefLabel
  • Intracoronary injection of autologous bone marrow-derived mononuclear cells in patients with large anterior acute myocardial infarction: a prematurely terminated randomized study
  • Intrakoronární injekce kmenových buněk kostní dřeně u pacientů s velkým předním infarktem myokardu: předčasně ukončená randomizovaná studie (cs)
  • Intracoronary injection of autologous bone marrow-derived mononuclear cells in patients with large anterior acute myocardial infarction: a prematurely terminated randomized study (en)
skos:notation
  • RIV/00216208:11120/07:00000646!RIV09-MZ0-11120___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NR8225), V, Z(MSM0021620817)
http://linked.open...iv/cisloPeriodika
  • 24
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 427329
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11120/07:00000646
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • bone marrow stem cells; myocardial infarction; left ventricular remodeling (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [1699988AD45F]
http://linked.open...i/riv/nazevZdroje
  • Journal of the American College of Cardiology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 49
http://linked.open...iv/tvurceVysledku
  • Kozák, Tomáš
  • Lang, Otto
  • Widimský, Petr
  • Horák, J.
  • Linhart, A.
  • Pytlík, R.
  • Kobylka, P.
  • Pěnička, Martin
  • Bělohlávek, Otakar
  • Paleček, T.
  • Aschermann, M.
  • Šimek, S.
  • Skalička, H.
http://linked.open...ain/vavai/riv/wos
  • 000247443200012
http://linked.open...n/vavai/riv/zamer
issn
  • 0735-1097
number of pages
http://localhost/t...ganizacniJednotka
  • 11120
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