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Description
| - Cílem studie bylo porovnat, zda jsou dietou indukované změny v inzulínové senzitivtě asociovány se změnami ve kvantitě polymerních izoforem adiponektinu. Celkem se 20 žen (věk 39.4+-;9.5 let; BMI, 32.2+- 6.4 kg/m2) podrobilo 12 týdenní nízkokalorické dietě. Adiponektin byl detekován pomocí western blotu. Pozorovali jsme zvýšení kvantity HMW? MMW i LMW formy adiponectinu o 5.5, 8.5 and 18.1% (p<0.05). celkový adiponektin se po intervenci snížil o 36% (P=0.08) (cs)
- Adiponectin is involved in the regulation of glucose and fatty acid metabolism, influences wholebody insulin sensitivity and protects arterial walls against the development of atherosclerosis. Plasma adiponectin is decreased in obese, insulin-resistant and Type 2 diabetic patients. Adiponectin circulates in plasma as high-, medium- and low-molecular mass forms (HMW, MMW and LMW respectively). The HMW form is believed to be closely associated with insulin sensitivity. The aim of the present study was to investigate whether diet-induced changes in body weight and insulin sensitivity were associated with changes in the quantity of adiponectin multimeric complexes. A total of 20 overweight or obese women (age, 39.4+-9.5 years; body mass index, 32.2+- 6.4 kg/m2) underwent 12 weeks of low caloric diet (600 kcal/day less than energy requirements; where 1 kcal≈4.184 kJ). Plasma samples were drawn before and after the study for biochemical analysis andWestern blot detection of adiponectin multimeric
- Adiponectin is involved in the regulation of glucose and fatty acid metabolism, influences wholebody insulin sensitivity and protects arterial walls against the development of atherosclerosis. Plasma adiponectin is decreased in obese, insulin-resistant and Type 2 diabetic patients. Adiponectin circulates in plasma as high-, medium- and low-molecular mass forms (HMW, MMW and LMW respectively). The HMW form is believed to be closely associated with insulin sensitivity. The aim of the present study was to investigate whether diet-induced changes in body weight and insulin sensitivity were associated with changes in the quantity of adiponectin multimeric complexes. A total of 20 overweight or obese women (age, 39.4+-9.5 years; body mass index, 32.2+- 6.4 kg/m2) underwent 12 weeks of low caloric diet (600 kcal/day less than energy requirements; where 1 kcal≈4.184 kJ). Plasma samples were drawn before and after the study for biochemical analysis andWestern blot detection of adiponectin multimeric (en)
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Title
| - An increase in plasma adiponectin multimeric complexes follows hypocaloric diet-induced pre-menopausal women
- Vzestup polymerních izoforem adiponektinu po váhovém úbytku navozeném hypokalorickou dietou u premenopauzálních žen (cs)
- An increase in plasma adiponectin multimeric complexes follows hypocaloric diet-induced pre-menopausal women (en)
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skos:prefLabel
| - An increase in plasma adiponectin multimeric complexes follows hypocaloric diet-induced pre-menopausal women
- Vzestup polymerních izoforem adiponektinu po váhovém úbytku navozeném hypokalorickou dietou u premenopauzálních žen (cs)
- An increase in plasma adiponectin multimeric complexes follows hypocaloric diet-induced pre-menopausal women (en)
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skos:notation
| - RIV/00216208:11120/07:00000291!RIV08-MSM-11120___
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216208:11120/07:00000291
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - obesity; adiponectin (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - GB - Spojené království Velké Británie a Severního Irska
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Kováčová, Zuzana
- Polák, Jan
- Samcová, Eva
- Šebela, M.
- Štich, Vladimír
- Klimčáková, Eva
- Kováčiková, Michaela
- Vítková, Michaela
- Jaček, Martin
- Kuda, O.
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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