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  • Brain neurotransmitters, serotonin and norepinephrine, play an important role in the central nervous control of energy balance and are involved in symptomatology related to both obesity and depression. Therefore both serotonin and norepinephrine neural pathways have been paid a special attention as targets for the antiobesity drugs, antidepressants, and drugs used in the treatment of eating disorders. Selective serotonin reuptake inhibitors (SSRI) have been used in the treatment of depression and eating disorders but have failed to achieve sustained weight loss in the treatment of obesity. Sibutramine, a serotonin and norepinephrine reuptake inhibitor, which induces satiety and prevents decline in metabolic rate associated with a hypocaloric diet, is currently the sole centrally acting drug indicated for the long-term treatment of obesity.
  • Brain neurotransmitters, serotonin and norepinephrine, play an important role in the central nervous control of energy balance and are involved in symptomatology related to both obesity and depression. Therefore both serotonin and norepinephrine neural pathways have been paid a special attention as targets for the antiobesity drugs, antidepressants, and drugs used in the treatment of eating disorders. Selective serotonin reuptake inhibitors (SSRI) have been used in the treatment of depression and eating disorders but have failed to achieve sustained weight loss in the treatment of obesity. Sibutramine, a serotonin and norepinephrine reuptake inhibitor, which induces satiety and prevents decline in metabolic rate associated with a hypocaloric diet, is currently the sole centrally acting drug indicated for the long-term treatment of obesity. (en)
Title
  • Serotonin and norepinephrine reuptake inhibiton and eating behavior
  • Serotonin and norepinephrine reuptake inhibiton and eating behavior (en)
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  • Serotonin and norepinephrine reuptake inhibiton and eating behavior
  • Serotonin and norepinephrine reuptake inhibiton and eating behavior (en)
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  • RIV/00216208:11120/06:00001588!RIV10-MSM-11120___
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  • 499002
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  • RIV/00216208:11120/06:00001588
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  • serotonin; norepinephrine; eating behavior; dietary disinhibition; sibutramine; abdominal obesity; metabolic syndrome (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [C46A25F51831]
http://linked.open...i/riv/nazevZdroje
  • Annals of the New York Academy of Sciences
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  • 1083
http://linked.open...iv/tvurceVysledku
  • Aldhoon, Bashar
  • Hainer, V.
  • Kunešová, M.
  • Wagenknecht, M.
  • Kabrnová, K.
http://linked.open...ain/vavai/riv/wos
  • 000244102900017
issn
  • 0077-8923
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  • 11120
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